M
M L Manco-Johnson
Researcher at University of Colorado Denver
Publications - 37
Citations - 3301
M L Manco-Johnson is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Autosomal dominant polycystic kidney disease & Polyhydramnios. The author has an hindex of 23, co-authored 37 publications receiving 3004 citations. Previous affiliations of M L Manco-Johnson include University of California, San Diego & University of Colorado Boulder.
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Journal ArticleDOI
Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia.
Marilyn J. Manco-Johnson,Marilyn J. Manco-Johnson,Thomas C. Abshire,Amy D. Shapiro,Brenda Riske,Michele R. Hacker,Ray F. Kilcoyne,J. David Ingram,M L Manco-Johnson,Sharon Funk,Linda J. Jacobson,Leonard A. Valentino,W. Keith Hoots,George R. Buchanan,Donna DiMichele,Michael Recht,Deborah L Brown,Cindy A. Leissinger,Shirley Bleak,Alan R. Cohen,Prasad Mathew,Alison Matsunaga,Desiree Medeiros,Diane J. Nugent,Gregory Thomas,Alexis A. Thompson,Kevin McRedmond,J. Michael Soucie,Harlan Austin,Bruce L. Evatt +29 more
TL;DR: Prophylaxis with recombinant factor VIII can prevent joint damage and decrease the frequency of joint and other hemorrhages in young boys with severe hemophilia A.
Journal ArticleDOI
Renal structure and hypertension in autosomal dominant polycystic kidney disease
Patricia A. Gabow,Arlene B. Chapman,Ann M. Johnson,Douglas J. Tangel,Irene T. Duley,William D. Kaehny,M L Manco-Johnson,Robert W. Schrier +7 more
TL;DR: The results indicate that the early high incidence of hypertension in ADPKD correlates with the renal structural abnormalities in this disorder.
Journal ArticleDOI
Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia.
Chengwen Li,Nattee Narkbunnam,Nattee Narkbunnam,Richard Jude Samulski,Aravind Asokan,Genlin Hu,L. J. Jacobson,M. J. Manco-Johnson,Paul E. Monahan,Marilyn J. Manco-Johnson,Brenda Riske,Ray F. Kilcoyne,M L Manco-Johnson,Sharon Funk,Linda J. Jacobson,J. David Ingram,Thomas C. Abshire,Thomas C. Abshire,Amy D. Shapiro,Michele R. Hacker,Leonard A. Valentino,W. Keith Hoots,Deborah L Brown,George R. Buchanan,Donna DiMichele,Michael Recht,Cindy A. Leissinger,Shirley Bleak,Alan R. Cohen,Prasad Mathew,Alison Matsunaga,Desiree Medeiros,Diane J. Nugent,Gregory Thomas,Alexis A. Thompson,Kevin McRedmond,J. Michael Soucie,Harlan Austin,Bruce L. Evatt +38 more
TL;DR: The results may guide rational design of clinical trials using alternative AAV serotypes and suggest that younger patients who are given AAV gene therapy will benefit from the lower prevalence of NAbs.
Journal ArticleDOI
The clinical utility of renal concentrating capacity in polycystic kidney disease.
Patricia A. Gabow,William D. Kaehny,Ann M. Johnson,Irene T. Duley,M L Manco-Johnson,Dennis C. Lezotte,Robert W. Schrier +6 more
TL;DR: An algorithm for diagnostic screening for ADPKD utilizing blood pressure, serum creatinine and UOsm designed to maximize sensitivity is developed and would have spared 20% of unaffected subjects from the cost of ultrasound while failing to detect less than 2% of affected subjects.
Journal ArticleDOI
The spectrum of autosomal dominant polycystic kidney disease in children.
Godela M. Fick,Irene T. Duley,Ann M. Johnson,John D. Strain,M L Manco-Johnson,Patricia A. Gabow +5 more
TL;DR: Significant relationship between the severity of the renal structural involvement and the frequency of flank and back pain, hypertension, and impaired renal concentrating capacity was found, but GFR were not reduced in children with ADPKD and did not relate to structural severity.