M
Markus Aebi
Researcher at ETH Zurich
Publications - 248
Citations - 20199
Markus Aebi is an academic researcher from ETH Zurich. The author has contributed to research in topics: Glycosylation & Oligosaccharyltransferase. The author has an hindex of 69, co-authored 245 publications receiving 18572 citations. Previous affiliations of Markus Aebi include École Polytechnique Fédérale de Lausanne & University of Zurich.
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Journal ArticleDOI
Roles of N-Linked Glycans in the Endoplasmic Reticulum
Ari Helenius,Markus Aebi +1 more
TL;DR: From a process involved in cell wall synthesis in archaea and some bacteria, N-linked glycosylation has evolved into the most common covalent protein modification in eukaryotic cells.
Journal ArticleDOI
N-Linked Glycosylation in Campylobacter jejuni and Its Functional Transfer into E. coli
Michael Wacker,Dennis Linton,Paul G. Hitchen,Mihai Nita-Lazar,Stuart M. Haslam,Simon J. North,Maria Panico,Howard R. Morris,Anne Dell,Brendan W. Wren,Markus Aebi +10 more
TL;DR: It is demonstrated that a functional N-linked glycosylation pathway could be transferred into Escherichia coli and opened up the possibility of engineering permutations of recombinant glycan structures for research and industrial applications.
Journal ArticleDOI
Symbol Nomenclature for Graphical Representations of Glycans.
Ajit Varki,Richard D. Cummings,Markus Aebi,Packer Nh,Peter H. Seeberger,Jeffrey D. Esko,Pamela Stanley,Gerald W. Hart,Alan G. Darvill,Taroh Kinoshita,James J. Prestegard,Ronald L. Schnaar,Hudson H. Freeze,Jamey D. Marth,Carolyn R. Bertozzi,Marilynn E. Etzler,Martin Frank,Johannes F.G. Vliegenthart,Thomas Lütteke,Serge Pérez,Evan E Bolton,Pauline M. Rudd,James C. Paulson,Minoru Kanehisa,Philip V. Toukach,Kiyoko F. Aoki-Kinoshita,Anne Dell,Hisashi Narimatsu,William S. York,Naoyuki Taniguchi,Stuart Kornfeld +30 more
TL;DR: Author(s): Varki, Ajit; Cummings, Richard D; Aebi, Markus; Packer, Nicole H; Seeberger, Peter H; Esko, Jeffrey D; Stanley, Pamela; Hart, Gerald; Darvill, Alan; Kinoshita, Taroh; Prestegard, James J; Schnaar, Ronald L; Freeze, Hudson H; Marth, Jamey D; Bertozzi, Carolyn R.
Journal ArticleDOI
The dolichol pathway of N-linked glycosylation
Patricie Burda,Markus Aebi +1 more
TL;DR: It is suggested that N-linked glycosylation in eukaryotes and in archaea share a common evolutionary origin and the function of the lipid carrier dolichol in oligosaccharide assembly is discussed.
Journal ArticleDOI
Mechanisms and principles of N-linked protein glycosylation.
Flavio Schwarz,Markus Aebi +1 more
TL;DR: This review discusses the highly conserved processes at the basis of this unique general protein modification system, characterized by a high structural diversity of N-linked glycans found among different species and by a large number of proteins that are glycosylated.