M
Markus R. Wenk
Researcher at National University of Singapore
Publications - 332
Citations - 25285
Markus R. Wenk is an academic researcher from National University of Singapore. The author has contributed to research in topics: Medicine & Lipid metabolism. The author has an hindex of 81, co-authored 292 publications receiving 21516 citations. Previous affiliations of Markus R. Wenk include Swiss Tropical and Public Health Institute & University of Geneva.
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Journal ArticleDOI
The identification of antioxidants in dark soy sauce
Huansong Wang,Andrew M. Jenner,Chung-Yung J. Lee,Guanghou Shui,Soon Yew Tang,Matthew Whiteman,Markus R. Wenk,Barry Halliwell +7 more
TL;DR: Structural characteristics based on nuclear magnetic resonance (NMR) and electrospray-ionization time-of-flight mass spectrometry (ESI-TOF-MS) analysis suggest that carbohydrate-containing pigments such as melanoidins are the major contributors to the high antioxidant capacity of DSS.
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Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals.
Yasuo Nemoto,Markus R. Wenk,Masami Watanabe,Laurie Daniell,Tomoe Murakami,Niels Ringstad,Hiroshi Yamada,Kohji Takei,Pietro De Camilli +8 more
TL;DR: It is suggested that synaptojanin 2B has a partially overlapping function with synaptoyanin 1 in nerve terminals, with additional roles in neurons and other cells including spermatids.
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A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila.
Katja Köhler,Erich Brunner,Xue Li Guan,Karin Boucke,Urs F. Greber,Sonali Mohanty,Julia Maria Isis Barth,Markus R. Wenk,Ernst Hafen +8 more
TL;DR: A proteomics approach is used to identify components of starvation-induced autophagic responses in the Drosophila fat body and proposes that Desat1 exerts its role in autophagy by controlling lipid biosynthesis and/or signaling necessary for autophotic responses.
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Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease
Lynette Lim,V Jackson-Lewis,L C Wong,Guanghou Shui,A X H Goh,S Kesavapany,Andrew M. Jenner,Andrew M. Jenner,Marc Fivaz,S Przedborski,Markus R. Wenk,Markus R. Wenk +11 more
TL;DR: It is found that lanosterol induces mild depolarization of mitochondria and promotes autophagy, and this results highlight a novel sterol-based neuroprotective mechanism with direct relevance to PD.
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Derivatization-independent cholesterol analysis in crude lipid extracts by liquid chromatography/mass spectrometry: applications to a rabbit model for atherosclerosis.
Guanghou Shui,Wei Fun Cheong,Ignasius A. Jappar,Aina Hoi,Yangkui Xue,Aaron Z. Fernandis,B. K. H. Tan,Markus R. Wenk +7 more
TL;DR: A derivatization-independent method for analyzing various sterols, including cholesterol and its congeners, using liquid chromatography and atmospheric pressure chemical ionization mass spectrometry, which indicated dramatic increases of the ratio of ergosterol esters to free ergosterols in Saccharomyces cerevisiae, which is consistent with the function of the respective enzymes.