M
Matthieu Camus
Researcher at French Institute of Health and Medical Research
Publications - 7
Citations - 8104
Matthieu Camus is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 6, co-authored 7 publications receiving 7130 citations. Previous affiliations of Matthieu Camus include Pierre-and-Marie-Curie University & Paris Descartes University.
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Journal ArticleDOI
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
Jérôme Galon,Anne Costes,Fátima Sánchez-Cabo,Amos Kirilovsky,Bernhard Mlecnik,Christine Lagorce-Pagès,Marie Tosolini,Matthieu Camus,Anne Berger,Philippe Wind,Franck Zinzindohoué,Patrick Bruneval,Paul-Henri Cugnenc,Zlatko Trajanoski,Wolf H. Fridman,Franck Pagès +15 more
TL;DR: In situ analysis of tumor-infiltrating immune cells may be a valuable prognostic tool in the treatment of colorectal cancer and possibly other malignancies.
Journal ArticleDOI
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
Franck Pagès,Anne Berger,Matthieu Camus,Fátima Sánchez-Cabo,Anne Costes,Robert Molidor,Bernhard Mlecnik,Amos Kirilovsky,Malin Nilsson,Diane Damotte,Tchao Meatchi,Patrick Bruneval,Paul-Henri Cugnenc,Zlatko Trajanoski,Wolf H. Fridman,Jérôme Galon +15 more
TL;DR: Signs of an immune response within colorectal cancers are associated with the absence of pathological evidence of early metastatic invasion and with prolonged survival.
Journal ArticleDOI
Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.
Bernhard Mlecnik,Marie Tosolini,Marie Tosolini,Marie Tosolini,Pornpimol Charoentong,Amos Kirilovsky,Amos Kirilovsky,Amos Kirilovsky,Gabriela Bindea,Anne Berger,Matthieu Camus,Matthieu Camus,Matthieu Camus,Mélanie Gillard,Mélanie Gillard,Mélanie Gillard,Patrick Bruneval,Wolf H. Fridman,Franck Pagès,Zlatko Trajanoski,Jérôme Galon +20 more
TL;DR: Data integration and biomolecular network reconstruction is a powerful approach to uncover molecular mechanisms in colorectal cancer and shows the utility of this approach for the investigation of malignant tumors and other diseases.
Journal ArticleDOI
Coordination of intratumoral immune reaction and human colorectal cancer recurrence.
Matthieu Camus,Marie Tosolini,Bernhard Mlecnik,Franck Pagès,Amos Kirilovsky,Anne Berger,Anne Costes,Gabriela Bindea,Pornpimol Charoentong,Patrick Bruneval,Zlatko Trajanoski,Wolf H. Fridman,Jérôme Galon +12 more
TL;DR: It is shown that the coexpression of genes mediating cytotoxicity (GNLY) and Th1 adaptive immune responses (IRF1) accurately predicted patient survival independently of the metastatic status, and high intratumoral mRNA expression of the proangiogenic mediator vascular endothelial growth factor was associated with significantly reduced survival rates in patients expressing high mRNA levels of GNLY.
Journal ArticleDOI
Activation of the Receptor NKG2D Leads to Production of Th17 Cytokines in CD4+ T Cells of Patients With Crohn's Disease
Benjamin Pariente,Iulia Mocan,Matthieu Camus,Charles-Antoine Dutertre,Julien Ettersperger,Pierre Cattan,Jean Marc Gornet,Nicolas Dulphy,Dominique Charron,Marc Lémann,Antoine Toubert,Matthieu Allez,Matthieu Allez +12 more
TL;DR: NKG2D is a functional marker of CD4+ T cells that produce IL-17 in patients with CD, via costimulation of the TCR and NKG1D and the T-cell receptor.