M
Marie Tosolini
Researcher at French Institute of Health and Medical Research
Publications - 67
Citations - 18158
Marie Tosolini is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Immune system & Cancer. The author has an hindex of 23, co-authored 61 publications receiving 13961 citations. Previous affiliations of Marie Tosolini include Pierre-and-Marie-Curie University & Paul Sabatier University.
Papers
More filters
Journal ArticleDOI
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
Jérôme Galon,Anne Costes,Fátima Sánchez-Cabo,Amos Kirilovsky,Bernhard Mlecnik,Christine Lagorce-Pagès,Marie Tosolini,Matthieu Camus,Anne Berger,Philippe Wind,Franck Zinzindohoué,Patrick Bruneval,Paul-Henri Cugnenc,Zlatko Trajanoski,Wolf H. Fridman,Franck Pagès +15 more
TL;DR: In situ analysis of tumor-infiltrating immune cells may be a valuable prognostic tool in the treatment of colorectal cancer and possibly other malignancies.
Journal ArticleDOI
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
Gabriela-Luana Bindea,Bernhard Mlecnik,Hubert Hackl,Pornpimol Charoentong,Marie Tosolini,Amos Kirilovsky,Wolf H. Fridman,Franck Pagès,Zlatko Trajanoski,Jérôme Galon +9 more
TL;DR: ClueGO is an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes and creates a functionally organized GO/pathway term network.
Journal ArticleDOI
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.
Gabriela Bindea,Bernhard Mlecnik,Bernhard Mlecnik,Bernhard Mlecnik,Marie Tosolini,Marie Tosolini,Marie Tosolini,Amos Kirilovsky,Amos Kirilovsky,Amos Kirilovsky,Maximilian J. Waldner,Anna C. Obenauf,Helen K. Angell,Helen K. Angell,Helen K. Angell,Tessa Fredriksen,Tessa Fredriksen,Tessa Fredriksen,Lucie Lafontaine,Lucie Lafontaine,Lucie Lafontaine,Anne Berger,Patrick Bruneval,Wolf H. Fridman,Wolf H. Fridman,Wolf H. Fridman,Christoph Becker,Franck Pagès,Michael R. Speicher,Zlatko Trajanoski,Jérôme Galon +30 more
TL;DR: The immune landscape in human colorectal cancer is revealed and the major hallmarks of the microenvironment associated with tumor progression and recurrence are revealed.
Journal ArticleDOI
Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer
Marie Tosolini,Amos Kirilovsky,Bernhard Mlecnik,Tessa Fredriksen,Stéphanie Mauger,Gabriela Bindea,Anne Berger,Patrick Bruneval,Wolf H. Fridman,Franck Pagès,Jérôme Galon +10 more
TL;DR: It is argued that functional Th1 and Th17 clusters yield opposite effects on patient survival in colorectal cancer, and they provide complementary information that may improve prognosis.
Journal ArticleDOI
Histopathologic-Based Prognostic Factors of Colorectal Cancers Are Associated With the State of the Local Immune Reaction
Bernhard Mlecnik,Marie Tosolini,Amos Kirilovsky,Anne Berger,Gabriela Bindea,Tchao Meatchi,Patrick Bruneval,Zlatko Trajanoski,Wolf H. Fridman,Franck Pagès,Jérôme Galon +10 more
TL;DR: Assessment of CD8(+) cytotoxic T lymphocytes in combined tumor regions provides an indicator of tumor recurrence beyond that predicted by AJCC/UICC-TNM staging.