M
Maurine Tong
Researcher at University of California, Los Angeles
Publications - 10
Citations - 3232
Maurine Tong is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Single-nucleotide polymorphism & TCF7L2. The author has an hindex of 6, co-authored 10 publications receiving 3130 citations. Previous affiliations of Maurine Tong include National Institutes of Health.
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Journal ArticleDOI
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
Laura J. Scott,Karen L. Mohlke,Lori L. Bonnycastle,Cristen J. Willer,Yun Li,William L. Duren,Michael R. Erdos,Heather M. Stringham,Peter S. Chines,Anne U. Jackson,Ludmila Prokunina-Olsson,Chia-Jen Ding,Amy J. Swift,Narisu Narisu,Tianle Hu,Randall Pruim,Rui Xiao,Xiao-Yi Li,Karen N. Conneely,Nancy Riebow,Andrew G. Sprau,Maurine Tong,Peggy P. White,Kurt N. Hetrick,Michael W. Barnhart,Craig W. Bark,Janet L. Goldstein,Lee Watkins,Fang Xiang,Jouko Saramies,Thomas A. Buchanan,Richard M. Watanabe,Timo T. Valle,Leena Kinnunen,Gonçalo R. Abecasis,Elizabeth W. Pugh,Kimberly F. Doheny,Richard N. Bergman,Jaakko Tuomilehto,Francis S. Collins,Michael Boehnke +40 more
TL;DR: The number of T2D loci now confidently identified to at least 10 is confirmed, and it is confirmed that variants near TCF7L2, SLC30A8, HHEX, FTO, PPARG, and KCNJ11 are associated with T1D risk.
Journal ArticleDOI
Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes.
Cristen J. Willer,Lori L. Bonnycastle,Karen N. Conneely,William L. Duren,Anne U. Jackson,Laura J. Scott,Narisu Narisu,Peter S. Chines,Andrew D. Skol,Heather M. Stringham,John Petrie,Michael R. Erdos,Amy J. Swift,Sareena T. Enloe,Andrew G. Sprau,Eboni Smith,Maurine Tong,Kimberly F. Doheny,Elizabeth W. Pugh,Richard M. Watanabe,Thomas A. Buchanan,Timo T. Valle,Richard N. Bergman,Jaakko Tuomilehto,Jaakko Tuomilehto,Karen L. Mohlke,Francis S. Collins,Michael Boehnke +27 more
TL;DR: The replication of 12 SNPs of 114 tested was significantly greater than expected by chance under the null hypothesis of no association, and SNPs from genes that had three or more previous reports of association were significantly more likely to be replicated in this sample.
Journal ArticleDOI
Comprehensive Association Study of Type 2 Diabetes and Related Quantitative Traits With 222 Candidate Genes
Kyle J. Gaulton,Cristen J. Willer,Yun Li,Laura J. Scott,Karen N. Conneely,Anne U. Jackson,William L. Duren,Peter S. Chines,Narisu Narisu,Lori L. Bonnycastle,Jingchun Luo,Maurine Tong,Andrew G. Sprau,Elizabeth W. Pugh,Kimberly F. Doheny,Timo T. Valle,Gonçalo R. Abecasis,Jaakko Tuomilehto,Jaakko Tuomilehto,Richard N. Bergman,Francis S. Collins,Michael Boehnke,Karen L. Mohlke +22 more
TL;DR: This study provides an effective gene-based approach to association study design and analysis and implicated novel genes, including RAPGEF1 and TP53, in type 2 diabetes susceptibility.
Journal ArticleDOI
Tissue-specific alternative splicing of TCF7L2.
Ludmila Prokunina-Olsson,Cullan Welch,Ola Hansson,Neeta Adhikari,Laura J. Scott,Nicolle Usher,Maurine Tong,Andrew G. Sprau,Amy J. Swift,Lori L. Bonnycastle,Michael R. Erdos,Zhi He,Richa Saxena,Brennan Harmon,Olga Kotova,Eric P. Hoffman,David Altshuler,Leif Groop,Michael Boehnke,Francis S. Collins,Jennifer L. Hall +20 more
TL;DR: No association between expression of TCF7L2 in eight types of human tissue samples and T2D-associated genetic variants remained significant, and a tissue-specific pattern of alternative splicing was identified.
Journal ArticleDOI
Discovery-Based Science Education: Functional Genomic Dissection in Drosophila by Undergraduate Researchers
Jiong Chen,Gerald B. Call,Elsa Beyer,Christopher N.H. Bui,Albert Cespedes,Amy M. Chan,Jenny Chan,Stacy Chan,Akanksha Chhabra,Peter Dang,Artemis Deravanesian,Brenda Hermogeno,James Jen,Eunha Kim,Eric Lee,Gemma Lewis,Jamie L. Marshall,Kirsten Regalia,Farnaz Shadpour,Aram Shemmassian,Kristin Spivey,Maggie Wells,Joy Wu,Yuki Yamauchi,Amir Yavari,Anna L. Abrams,Amanda Abramson,Latiffe Amado,Jenny Anderson,Keenan Bashour,Elena Bibikova,Allen Bookatz,Sarah Brewer,Natalie Buu,Stephanie Calvillo,Joseph Cao,Aileen Chang,Daniel Chang,Yuli Chang,Yibing Chen,Joo Choi,Jeyling Chou,Sumit Datta,Ardy Davarifar,Poonam Desai,Jordan Fabrikant,Shahbaz Farnad,Katherine Fu,Eddie Garcia,Nick Garrone,Srpouhi Gasparyan,Phyllis Gayda,Chad Goffstein,Courtney Gonzalez,Mariam Guirguis,Ryan Hassid,Aria Hong,Julie Hong,Lindsay Hovestreydt,Charles Hu,Farid Jamshidian,Katrin Kahen,Linda Kao,Melissa M. Kelley,Thomas Kho,Sarah Kim,Yein Kim,Brian Kirkpatrick,Emil Kohan,Robert Kwak,Adam D. Langenbacher,Santino Laxamana,Christopher Lee,Janet Lee,So-Youn Lee,To Hang S Lee,Toni Lee,Sheila Lezcano,Henry Lin,Peter Lin,Julie Luu,Thanh Luu,William R. Marrs,Erin Marsh,Sarah Min,Tanya Minasian,Amit Misra,Miles Morimoto,Yasaman Moshfegh,Jessica Murray,Cynthia Nguyen,Kha Nguyen,Ernesto Nodado,Amanda O'Donahue,Ndidi Onugha,Nneka Orjiakor,Bhavin Padhiar,Mara Pavel-Dinu,Alex Pavlenko,Edwin Paz,Sarah Phaklides,Lephong Pham,Preethi Poulose,Russell Powell,Aya Pusic,Divi Ramola,Meghann Ribbens,Bassel Rifai,Desiree Rosselli,Manyak Saakyan,Pamela Saarikoski,Miriam Segura,Ramnik Singh,Vivek Singh,Emily Skinner,Daniel Solomin,Kosha Soneji,Erika Stageberg,Marina Stavchanskiy,Leena Tekchandani,Leo Thai,Jayantha Thiyanaratnam,Maurine Tong,Aneet Toor,Steve Tovar,Kelly Trangsrud,Wah-Yung Tsang,Marc Uemura,Mary Unkovic,Emily Vollmer,Emily Weiss,Damien Wood,Sophia Wu,Winston Wu,Qing Xu,Kevin Yackle,Will Yarosh,Laura Yee,George Yen,Grant Alkin,Sheryllene Go,Devon M Huff,Helena Minye,Eric Paul,Nikki Villarasa,Allison Milchanowski,Utpal Banerjee +146 more
TL;DR: The UCLA Undergraduate Consortium for Functional Genomics provides the answer to how to combine professional-quality research with discovery-based undergraduate education.