Meritxell Genescà

TL;DR: The results validate the use of the RNA FISH/flow technique to assess the potency of LRAs among different CD4+ T cell subsets, manifest the intrinsic differences between cells that encompass the latent HIV reservoir, and highlight the difficulty to significantly impact the latent infection with the currently available drugs.

TL;DR: CD32 is not a marker of resting CD4+ T cells or of enriched HIV DNA–positive cells after ART; rather, CD32 is predominately expressed on a subset of activated CD4- T cells enriched for transcriptionally active HIV after long-term ART.

TL;DR: Two pathways define the role of NOS/NO systems in the development of apoptosis during experimental renal I/R: a direct route through eNOS overexpression and NO production, and an indirect route, through expression/activation of the iNos/NO system, induced by eN OS.

TL;DR: Observations indicate that antiviral antibody responses are critical in maintaining effective control of SIV replication at early time points postinfection.

TL;DR: In this paper, the authors identify circulating virus-specific T cell responses during acute infection with functional, migratory and apoptotic patterns modulated by viral proteins and associated with clinical outcome, highlighting a balanced anti-inflammatory antiviral response associated with a better outcome and persisting TRM cells as important for future protection against SARS-CoV-2 infection.