M
Michael J. Arrowood
Researcher at Centers for Disease Control and Prevention
Publications - 119
Citations - 7772
Michael J. Arrowood is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Cryptosporidium parvum & Cryptosporidium. The author has an hindex of 45, co-authored 118 publications receiving 7213 citations. Previous affiliations of Michael J. Arrowood include United States Department of Health and Human Services & Kansas State University.
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Journal ArticleDOI
A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium
William Checkley,William Checkley,A. Clinton White,Devan Jaganath,Michael J. Arrowood,Rachel M. Chalmers,Xian Ming Chen,Ronald Fayer,Jeffrey K. Griffiths,Richard L. Guerrant,Lizbeth Hedstrom,Christopher D. Huston,Karen L. Kotloff,Gagandeep Kang,Jan R. Mead,Jan R. Mead,Mark A. Miller,William A. Petri,Jeffrey W. Priest,David S. Roos,Boris Striepen,R.C. Andrew Thompson,Honorine D. Ward,Wesley A. Van Voorhis,Lihua Xiao,Guan Zhu,Eric R. Houpt +26 more
TL;DR: Use of cryptosporidium genomes has helped to identify promising therapeutic targets, and drugs are in development, but methods to assess the efficacy in vitro and in animals are not well standardised.
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Genetic diversity within cryptosporidium parvum and related cryptosporidium species
Lihua Xiao,Una M. Morgan,Josef Limor,Ananias A. Escalante,Michael J. Arrowood,William P. Shulaw,R.C.A. Thompson,Ronald Fayer,Altaf A. Lal +8 more
TL;DR: A need for revision in the taxonomy and assessment of the zoonotic potential of some animal C. parvum isolates is indicated, because extensive genetic diversities were present among C. Parvum genotypes.
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Isolation of Cryptosporidium oocysts and sporozoites using discontinuous sucrose and isopycnic Percoll gradients.
TL;DR: Techniques for the large-scale isolation of Cryptosporidium oocysts and sporozoites, obtained from the feces of experimentally infected Holstein calves, were developed employing discontinuous sucrose gradients and isopycnic Percoll gradients.
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Genetic polymorphism among cryptosporidium parvum isolates: evidence of two distinct human transmission cycles
Peng Mm,Lihua Xiao,A. R. Freeman,Michael J. Arrowood,Ananias A. Escalante,Andre Weltman,Corinne S. L. Ong,Mac Kenzie Wr,A.A. Lal,Charles B. Beard +9 more
TL;DR: The results of molecular analysis of 39 isolates of Cryptosporidium parvum from human and bovine sources in nine human outbreaks and from bovines from a wide geographic distribution support the occurrence of two distinct transmission cycles of C. parVum in humans.
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New cryptosporidium genotypes in HIV-infected persons.
Norman J. Pieniazek,Fernando J. Bornay-Llinares,Susan B. Slemenda,A J da Silva,Iaci N. S. Moura,Michael J. Arrowood,O. Ditrich,D. G. Addiss +7 more
TL;DR: Using DNA sequencing and phylogenetic analysis, the authors identified four distinct Cryptosporidium genotypes in HIV-infected patients: genotype 1 (human), genotype 2 (bovine) CryptoSporidium parvum, a genotype identical to C. felis, and one identical to a Cryptospora sp. isolate from a dog.