D
Devan Jaganath
Researcher at University of California, San Francisco
Publications - 51
Citations - 2297
Devan Jaganath is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 17, co-authored 40 publications receiving 1859 citations. Previous affiliations of Devan Jaganath include Johns Hopkins University & University of California, Los Angeles.
Papers
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Journal ArticleDOI
A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium
William Checkley,William Checkley,A. Clinton White,Devan Jaganath,Michael J. Arrowood,Rachel M. Chalmers,Xian Ming Chen,Ronald Fayer,Jeffrey K. Griffiths,Richard L. Guerrant,Lizbeth Hedstrom,Christopher D. Huston,Karen L. Kotloff,Gagandeep Kang,Jan R. Mead,Jan R. Mead,Mark A. Miller,William A. Petri,Jeffrey W. Priest,David S. Roos,Boris Striepen,R.C. Andrew Thompson,Honorine D. Ward,Wesley A. Van Voorhis,Lihua Xiao,Guan Zhu,Eric R. Houpt +26 more
TL;DR: Use of cryptosporidium genomes has helped to identify promising therapeutic targets, and drugs are in development, but methods to assess the efficacy in vitro and in animals are not well standardised.
Journal ArticleDOI
Sleep deprivation impairs cAMP signalling in the hippocampus
Christopher G. Vecsey,George S. Baillie,Devan Jaganath,Robbert Havekes,Andrew Daniels,Mathieu E. Wimmer,Ted Huang,Kim M. Brown,Xiang-Yao Li,Giannina Descalzi,Susan S. Kim,Tao Chen,Yuze Shang,Min Zhuo,Miles D. Houslay,Ted Abel +15 more
TL;DR: It is demonstrated that brief sleep deprivation disrupts hippocampal function by interfering with cAMP signalling through increased PDE4 activity, and drugs that enhance camp signalling may provide a new therapeutic approach to counteract the cognitive effects of sleep deprivation.
Journal ArticleDOI
Social Networking Technologies as an Emerging Tool for HIV Prevention: A Cluster Randomized Trial
Sean D. Young,William G. Cumberland,Sung-Jae Lee,Devan Jaganath,Greg Szekeres,Thomas J. Coates +5 more
TL;DR: Whether social networking communities can increase HIV testing among African American and Latino men who have sex with men (MSM) and whether these communities are acceptable and effective tools to increase home-based HIVTesting among at-risk populations is investigated.
Journal ArticleDOI
Childhood Tuberculosis and Malnutrition
TL;DR: There is a critical need for research on childhood tuberculosis, specifically on how nutritional status affects the risk and progression of tuberculosis and whether nutritional supplementation improves clinical outcomes or prevents disease.
Journal ArticleDOI
Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus
Christopher G. Vecsey,Lucia Peixoto,Jennifer H. K. Choi,Mathieu E. Wimmer,Devan Jaganath,Pepe J. Hernandez,Jennifer M. Blackwell,Karuna Meda,Alan J. Park,Sridhar Hannenhalli,Ted Abel +10 more
TL;DR: The findings suggest that the detrimental effects of sleep deprivation may be mediated by reductions in protein synthesis via downregulation of mTOR, a key regulator of protein synthesis.