Guan Zhu

TL;DR: Genome analysis identifies extremely streamlined metabolic pathways and a reliance on the host for nutrients in the parasite, which lacks an apicoplast and its genome, and possesses a degenerate mitochondrion that has lost its genome.

TL;DR: Use of cryptosporidium genomes has helped to identify promising therapeutic targets, and drugs are in development, but methods to assess the efficacy in vitro and in animals are not well standardised.

TL;DR: The current understanding of teleost immune-relevant genes for both innate and adaptive immunity, including pattern recognition receptors, antimicrobial peptides, complement molecules, lectins, interferons and signaling factors, inflammatory cytokines, chemokines, adaptive immunity relevant cytokines and negative regulators are discussed.

TL;DR: Primers based upon the highly conserved plastid small- or large-subunit rRNA and the tufA-tRNAPhe genes of other members of the phylum Apicomplexa failed to amplify products from intracellular stages of C. parvum, suggesting an alternative evolutionary fate for this organelle in one member of the ApicOMplexa.

TL;DR: A review of the biology, biochemistry and host parasite relationships of Cryptosporidium can be found in this paper, where the authors highlight the uniqueness of this organism in terms of its parasite life style and evolutionary biology.