M
Michaela Golic
Researcher at Charité
Publications - 37
Citations - 775
Michaela Golic is an academic researcher from Charité. The author has contributed to research in topics: Preeclampsia & Pregnancy. The author has an hindex of 12, co-authored 37 publications receiving 568 citations. Previous affiliations of Michaela Golic include Max Delbrück Center for Molecular Medicine & Humboldt University of Berlin.
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Journal ArticleDOI
Targeting CpG Oligonucleotides to the Lymph Node by Nanoparticles Elicits Efficient Antitumoral Immunity
Carole Bourquin,David Anz,Klaus Zwiorek,Anna-Lisa Lanz,Sebastian Fuchs,Sarah Weigel,Cornelia Wurzenberger,Philip von der Borch,Michaela Golic,Stefan Moder,Gerhard Winter,Conrad Coester,Stefan Endres +12 more
TL;DR: A novel strategy to target immunostimulatory oligonucleotides to the initiation site of the immune response while at the same time protecting from an indiscriminate and generalized activation of theimmune system is described.
Journal ArticleDOI
CD103 is a hallmark of tumor-infiltrating regulatory T cells
David Anz,Wolfgang Mueller,Michaela Golic,Wolfgang G. Kunz,Moritz Rapp,Viktor H. Koelzer,Jonathan Ellermeier,Joachim W. Ellwart,Max Schnurr,Carole Bourquin,Stefan Endres +10 more
TL;DR: In this article, an integrin mediating lymphocyte retention in epithelial tissues, is expressed at high levels on tumor-infiltrating FoxP3+ Treg in several types of murine cancer.
Journal ArticleDOI
Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants
Hong Wa Yung,Patji Alnæs-Katjavivi,Carolyn J.P. Jones,Tatiana El-Bacha,Michaela Golic,Anne-Cathrine Staff,Graham J. Burton +6 more
TL;DR: This is the first report of placental ER stress in GDM patients and chemical chaperones and antioxidant vitamins represent potential therapeutic interventions for GDM.
Journal ArticleDOI
CD74-Downregulation of Placental Macrophage-Trophoblastic Interactions in Preeclampsia.
Lukasz Przybyl,Nadine Haase,Michaela Golic,Julianna Rugor,Maria Emilia Solano,Petra C. Arck,Martin Gauster,Berthold Huppertz,Christoph Emontzpohl,Christian Stoppe,Jürgen Bernhagen,Lin Leng,Richard Bucala,Herbert Schulz,Arnd Heuser,M. Susanne Weedon-Fekjær,Guro M. Johnsen,Dirk Peetz,Friedrich C. Luft,Anne Cathrine Staff,Dominik N. Müller,Ralf Dechend,Florian Herse +22 more
TL;DR: It is hypothesized that cluster of differentiation 74 (CD74) downregulation on placental macrophages, leading to altered macrophage-trophoblast interaction, is involved in preeclampsia, which features hypertension, proteinuria, and placental anomalies.
Journal ArticleDOI
Suppression of intratumoral CCL22 by type i interferon inhibits migration of regulatory T cells and blocks cancer progression.
David Anz,Moritz Rapp,Stephan Eiber,Viktor H. Koelzer,Raffael Thaler,Sascha Haubner,Max M. L. Knott,Sarah Nagel,Michaela Golic,Gabriela M. Wiedemann,Franz Bauernfeind,Cornelia Wurzenberger,Veit Hornung,Christoph Scholz,Doris Mayr,Simon Rothenfusser,Stefan Endres,Carole Bourquin,Carole Bourquin +18 more
TL;DR: It is argued that type I IFN blocks the Treg-attracting chemokine CCL22 and thus helps limit the recruitment of Treg to tumors, a finding with implications for cancer immunotherapy.