M
Michelle R. Staudt
Researcher at Cornell University
Publications - 45
Citations - 1964
Michelle R. Staudt is an academic researcher from Cornell University. The author has contributed to research in topics: Population & Respiratory epithelium. The author has an hindex of 24, co-authored 45 publications receiving 1638 citations. Previous affiliations of Michelle R. Staudt include Virginia Commonwealth University & University of North Carolina at Chapel Hill.
Papers
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Journal ArticleDOI
Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling
Sang Hoon Sin,Debasmita Roy,Ling Wang,Michelle R. Staudt,Farnaz D. Fakhari,Dhavalkumar D. Patel,David H. Henry,William J. Harrington,Blossom Damania,Dirk P. Dittmer +9 more
TL;DR: It is found that sirolimus is efficacious against PEL in culture and in a murine xenograft model and addition of exogenous IL-10 or IL-6 can reverse the rapamycin growth arrest.
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Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity.
Matthew S. Walters,Kazunori Gomi,Beth Ashbridge,Malcolm A.S. Moore,Vanessa Arbelaez,Jonna Heldrich,Bi-Sen Ding,Shahin Rafii,Michelle R. Staudt,Ronald G. Crystal +9 more
TL;DR: Development of immortalized human airway BC that retain multipotent differentiation capacity over long-term culture should be useful in understanding the biology of BC, the response of BC to environmental stress, and as a target for assessment of pharmacologic agents.
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mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).
Irina V. Lebedeva,Luni Emdad,Zao Zhong Su,Pankaj Gupta,Moira Sauane,Devanand Sarkar,Michelle R. Staudt,Shi Jian Liu,Mohiuddin M. Taher,Ruoyu Xiao,Paola M. Barral,Seok-Geun Lee,Dongning Wang,Nicollaq Vozhilla,Eun Sook Park,Lejuan Chatman,Habib Boukerche,Rajagopal Ramesh,Satoshi Inoue,Sunil Chada,Rong Li,Anthony L. De Pass,Parameshwar J. Mahasreshti,Igor Dmitriev,David T. Curiel,Adly Yacoub,Steven Grant,Paul Dent,Neil Senzer,John Nemunaitis,Paul B. Fisher +30 more
TL;DR: The present review focuses on three unique properties of mda-7/IL-24, namely its potent 'bystander antitumor activity', ability to sensitize tumor cells to radiation, and its antiangiogenesis properties.
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Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression
Lauren J. Buro-Auriemma,Jacqueline Salit,Neil R. Hackett,Matthew S. Walters,Yael Strulovici-Barel,Michelle R. Staudt,Jennifer Fuller,Mai A. Mahmoud,Christopher S. Stevenson,Holly Hilton,Melisa W. Y. Ho,Ronald G. Crystal +11 more
TL;DR: Evidence is provided that cigarette smoking alters the DNA methylation patterning of the SAE and that, for some genes, these changes are associated with the smoking-related changes in gene expression.
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Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes.
TL;DR: This study provides in vivo human data demonstrating that acute inhalation of EC aerosols dysregulates normal human lung homeostasis in a limited cohort of healthy naïve individuals.