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Michelle Setterholm
Researcher at National Marrow Donor Program
Publications - Â 57
Citations - Â 5281
Michelle Setterholm is an academic researcher from National Marrow Donor Program. The author has contributed to research in topics: Transplantation & Human leukocyte antigen. The author has an hindex of 31, co-authored 57 publications receiving 4955 citations. Previous affiliations of Michelle Setterholm include Center for International Blood and Marrow Transplant Research.
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Journal ArticleDOI
High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation.
Stephanie J. Lee,John P. Klein,Michael Haagenson,Lee Ann Baxter-Lowe,Dennis L. Confer,Mary Eapen,Marcelo Fernandez-Vina,Neal Flomenberg,Mary M. Horowitz,Carolyn Katovich Hurley,Harriet Noreen,Machteld Oudshoorn,Effie W. Petersdorf,Michelle Setterholm,Stephen R. Spellman,Daniel J. Weisdorf,Thomas M. Williams,Claudio Anasetti +17 more
TL;DR: In multivariate modeling, patient age, race, disease stage, and cytomegalovirus status were as predictive of survival as donor HLA matching, and high-resolution DNA matching for HLA-A, -B, -C, and -DRB1 alleles is associated with higher rates of survival.
Journal ArticleDOI
Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome.
Neal Flomenberg,Lee Ann Baxter-Lowe,Dennis L. Confer,Marcelo Fernandez-Vina,Alexandra H. Filipovich,Mary M. Horowitz,Carolyn Katovich Hurley,Craig Kollman,Claudio Anasetti,Harriet Noreen,Ann B. Begovich,William H. Hildebrand,Effie W. Petersdorf,B.J. Schmeckpeper,Michelle Setterholm,Elizabeth Trachtenberg,Thomas N. Williams,Edmond J. Yunis,Daniel J. Weisdorf +18 more
TL;DR: It is concluded that matching for HLA-C should be incorporated into algorithms for unrelated donor selection, and when clinical circumstances allow, high-resolution class I typing may help optimize donor selection and improve outcome.
Journal ArticleDOI
The HLA dictionary 1999: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens.
Geziena M.Th. Schreuder,Carolyn Katovich Hurley,Steven G.E. Marsh,M. Lau,Marcelo Fernandez-Vina,Harriet Noreen,Michelle Setterholm,Martin Maiers +7 more
TL;DR: The equivalents provided will be useful in guiding searches for unrelated hematopoietic stem cell donors in which patients and/or potential donors are typed by either serology or DNA-based methods and will also serve typing and matching procedures for organ transplant programs where HLA typings from donors and from recipients on waiting lists represent mixtures of serologic and molecular typings.
Journal ArticleDOI
The effect of KIR ligand incompatibility on the outcome of unrelated donor transplantation: a report from the center for international blood and marrow transplant research, the European blood and marrow transplant registry, and the Dutch registry.
Sherif S. Farag,Andrea Bacigalupo,Mary Eapen,Carolyn Katovich Hurley,Bo Dupont,Michael A. Caligiuri,Christian Boudreau,Gene Nelson,Machteld Oudshoorn,Jon J. van Rood,Andrea Velardi,Martin Maiers,Michelle Setterholm,Dennis L. Confer,Phillip E. Posch,Claudio Anasetti,Naynesh Kamani,Jeffrey S. Miller,Daniel J. Weisdorf,Stella M. Davies +19 more
TL;DR: Patients who received grafts from donors mismatching at the KIR ligand in the GVH or HVG direction and mismatched at HLA-B and/or C but matched at the kir ligand had similar rates of TRM, treatment failure, and overall mortality.
Journal ArticleDOI
The effect of donor characteristics on survival after unrelated donor transplantation for hematologic malignancy
Craig Kollman,Stephen R. Spellman,Mei-Jie Zhang,Mei-Jie Zhang,Anna Hassebroek,Claudio Anasetti,Joseph H. Antin,Richard E. Champlin,Dennis L. Confer,John F. DiPersio,Marcelo Fernandez-Vina,Robert J. Hartzman,Mary M. Horowitz,Carolyn Katovich Hurley,Chatchada Karanes,Martin Maiers,Carlheinz Mueller,Miguel-Angel Perales,Michelle Setterholm,Ann E. Woolfrey,Neng Yu,Mary Eapen,Mary Eapen +22 more
TL;DR: Survival was better after transplantation of grafts from young donors (aged 18-32 years) who were HLA matched to recipients who were ABO matching to recipients (P < .001).