M
Mirko Pham
Researcher at University Hospital Heidelberg
Publications - 123
Citations - 4137
Mirko Pham is an academic researcher from University Hospital Heidelberg. The author has contributed to research in topics: Magnetic resonance neurography & Medicine. The author has an hindex of 32, co-authored 104 publications receiving 3262 citations. Previous affiliations of Mirko Pham include German Cancer Research Center & Heidelberg University.
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Journal ArticleDOI
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature
Christoph Kleinschnitz,Peter Kraft,Angela Dreykluft,Ina Hagedorn,Kerstin Göbel,Michael K. Schuhmann,Friederike Langhauser,Xavier Helluy,Tobias Schwarz,Stefan Bittner,Christian T. Mayer,Marc Brede,Csanad Varallyay,Mirko Pham,Martin Bendszus,Peter M. Jakob,Tim Magnus,Sven G. Meuth,Yoichiro Iwakura,Alma Zernecke,Tim Sparwasser,Bernhard Nieswandt,Guido Stoll,Heinz Wiendl +23 more
TL;DR: A novel and unexpected role of Tregs in a primary nonimmunologic disease state is defined, which reduced microvascular thrombus formation and improved cerebral reperfusion on stroke, as revealed by ultra-high-field magnetic resonance imaging at 17.6 Tesla.
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The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction
David Varga-Szabo,Attila Braun,Christoph Kleinschnitz,Markus Bender,Irina Pleines,Mirko Pham,Thomas Renné,Guido Stoll,Bernhard Nieswandt +8 more
TL;DR: STIM1 is established as an important mediator in the pathogenesis of ischemic cardio- and cerebrovascular events in mice with STIM1-deficient platelets, which are significantly protected from arterial thrombosis and isChemic brain infarction but have only a mild bleeding time prolongation.
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Anterior interosseous nerve syndrome: Fascicular motor lesions of median nerve trunk
Mirko Pham,Philipp Bäumer,Hans-Michael Meinck,Johannes Schiefer,Markus Weiler,Martin Bendszus,Henrich Kele +6 more
TL;DR: The data strongly support that AINS in the majority of cases is not a surgically treatable entrapment neuropathy but a multifocal mononeuropathy selectively involving, within the main trunk of the median nerve, the motor fascicles that continue distally to form the anterior interosseous nerve.
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Ulnar neuropathy at the elbow: MR neurography--nerve T2 signal increase and caliber.
Philipp Bäumer,Thomas Dombert,Frank Staub,Thorsten Kaestel,Andreas J. Bartsch,Sabine Heiland,Martin Bendszus,Mirko Pham +7 more
TL;DR: Nerve T2 signal increase seems to be an accurate sign to determine the presence of UNE, and nerve caliber enlargement discriminates severe from mild UNE.
Journal ArticleDOI
Prophylactic intravenous magnesium sulfate for treatment of aneurysmal subarachnoid hemorrhage: a randomized, placebo-controlled, clinical study.
Thomas Westermaier,Christian Stetter,Giles H. Vince,Mirko Pham,Jose Perez Tejon,Jörg Eriskat,Ekkehard Kunze,Cordula Matthies,Ralf-Ingo Ernestus,Laszlo Solymosi,Klaus Roosen +10 more
TL;DR: The data indicate that high-dose intravenous magnesium can reduce cerebral ischemic events after aneurysmal subarachnoid hemorrhage by attenuating vasospasm and increasing the isChemic tolerance during critical hypoperfusion.