M
Monica Manglani
Researcher at National Institutes of Health
Publications - 9
Citations - 531
Monica Manglani is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cytotoxic T cell & CD8. The author has an hindex of 6, co-authored 8 publications receiving 316 citations. Previous affiliations of Monica Manglani include Pennsylvania State University.
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Journal ArticleDOI
The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness.
Tuoqi Wu,Yun Ji,E. Ashley Moseman,Haifeng C. Xu,Monica Manglani,Martha Kirby,Stacie M. Anderson,Robin Handon,Elizabeth Kenyon,Abdel G. Elkahloun,Weiwei Wu,Philipp A. Lang,Luca Gattinoni,Dorian B. McGavern,Pamela L. Schwartzberg +14 more
TL;DR: Insight is provided into the requirements for persistence of T cell immune responses in the face of exhaustion and mechanisms by which effective T cell–mediated immunity may be enhanced during chronic infections and cancer are suggested.
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CD8+ T cells target cerebrovasculature in children with cerebral malaria
Brittany A. Riggle,Monica Manglani,Monica Manglani,Dragan Maric,Kory R. Johnson,Myoung-Hwa Lee,Osorio Abath Neto,Terrie E. Taylor,Terrie E. Taylor,Karl B. Seydel,Karl B. Seydel,Avindra Nath,Louis H. Miller,Dorian B. McGavern,Susan K. Pierce +14 more
TL;DR: Within the studied cohort, CM is associated with cerebrovascular engagement of CD3+CD8+ T cells, which is exacerbated by HIV coinfection, opening new avenues for the treatment of this deadly disease.
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New advances in CNS immunity against viral infection.
TL;DR: This review discusses recent advances in immune recruitment and entry at barrier structures as well as current immunotherapeutic strategies for the treatment of persistent viral infections.
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Leukocyte Isolation from Brain, Spinal Cord, and Meninges for Flow Cytometric Analysis
TL;DR: This protocol provides a method to isolate leukocytes from brain, spinal cord, and meninges for flow cytometric analysis and provides a basic framework for phenotyping these cells.
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Intravital Imaging of Neuroimmune Interactions Through a Thinned Skull.
TL;DR: This protocol provides guidance on how to create a thinned skull window without causing CNS injury and describes a highly reproducible method to induce a mild traumatic brain injury using the thinned skulls approach.