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Nancy Y. Ip
Researcher at Hong Kong University of Science and Technology
Publications - 390
Citations - 37404
Nancy Y. Ip is an academic researcher from Hong Kong University of Science and Technology. The author has contributed to research in topics: Cyclin-dependent kinase 5 & Neurotrophin. The author has an hindex of 78, co-authored 381 publications receiving 34323 citations. Previous affiliations of Nancy Y. Ip include University of Cambridge & Chinese Academy of Sciences.
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Regulation of the concentration of adenosine 3',5'-cyclic monophosphate and the activity of tyrosine hydroxylase in the rat superior cervical ganglion by three neuropeptides of the secretin family
TL;DR: A strong correlation was found between the cAMP level and the TH activity in individual ganglia exposed to these peptides, and 8-bromoadenosine 3′,5′-cyclic monophosphate and forskolin also increased TH activity.
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The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.
Yangui Xiao,Yinghui Peng,Jun Wan,Genyun Tang,Yuewen Chen,Yuewen Chen,Jing Tang,Wen-Cai Ye,Nancy Y. Ip,Nancy Y. Ip,Lei Shi,Lei Shi +11 more
TL;DR: This study identifies that Dock4 is critical for neurite differentiation and extension in neuroblastoma cells and hippocampal neurons and reveals that the SH3 domain-mediated interaction of Dock 4 is required for its activity toward neurites differentiation, whereas its proline-rich C terminus is not essential for this regulation.
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Eph receptors at synapses: Implications in neurodegenerative diseases
Yu Chen,Amy K.Y. Fu,Nancy Y. Ip +2 more
TL;DR: The emerging evidence implicating that deregulation of Eph/ephrin signaling contributes to the aberrant synaptic functions associated with cognitive impairment in Alzheimer's disease is discussed.
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Time course of ciliary neurotrophic factor mRNA expression is coincident with the presence of protoplasmic astrocytes in traumatized rat striatum.
TL;DR: Investigation of the time course of the astrocytic response in vivo and in vitro, and the expression of ciliary neurotrophic factor (CNTF) mRNA following striatal injury concludes that reactiveAstrocytes are likely candidates to produce the neurite promoting activity seen in previous studies after trauma in the striatum.
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Expression of the P2Y1 nucleotide receptor in chick muscle: its functional role in the regulation of acetylcholinesterase and acetylcholine receptor.
Roy Chi Yan Choi,Menlisa L.S. Man,Karen K. Y. Ling,Nancy Y. Ip,Joseph Simon,Eric A. Barnard,Karl Wah Keung Tsim +6 more
TL;DR: Evidence is provided for a novel function of ATP in regulating the gene expression of those two postsynaptic effectors: acetylcholinesterase and AChR in muscles, mediated by a metabotropic ATP receptor subtype, the P2Y1 receptor.