Nancy Y. Ip

TL;DR: CaMKv knockdown in mouse hippocampal CA1 pyramidal neurons impairs synaptic transmission and plasticity in vivo, resulting in hyperactivity and spatial memory impairment, which collectively indicate that the precise regulation of CaMKv through activity-dependent synthesis and post-translational phosphorylation is critical for dendritic spine maintenance.

TL;DR: The finding on the ability of tetrodotoxin to induce p35 transcript in muscle suggested that electrical activity could regulate p35 expression, and northern blot analysis revealed that Cdk5 and p35 transcripts were up-regulated in muscle after nerve denervation, suggest that Ckk5 and P35 may play important physiological roles in muscle regeneration following nerve injury.

TL;DR: In this paper, the use of Astragalus extracts in inducing telomerase activity in cells is described. But the authors focus on the application of plant extracts for treating diseases subject to treatment, such as HIV infection, various degenerative diseases, and acute or chronic skin ailments.

TL;DR: Cholinergic mechanisms for the acute regulation of tyrosine 3-monooxygenase may be activated in vivo by acetylcholine released from preganglionic neurons and thus may play a role in the physiological regulation of catecholamine synthesis in sympathetic ganglia.

TL;DR: Five new limonoids, toosendone and 12-ethoxynimbolinins A-D, isolated from the fruits of Melia toosendsan established significant antibacterial activity against the oral pathogen, Porphyromonas gingivalis ATCC 33 277.