N
Naomi Iwai
Researcher at Osaka University
Publications - 50
Citations - 2310
Naomi Iwai is an academic researcher from Osaka University. The author has contributed to research in topics: Biliary tract & Hirschsprung's disease. The author has an hindex of 16, co-authored 50 publications receiving 2163 citations. Previous affiliations of Naomi Iwai include Kyoto Prefectural University of Medicine & Tohoku University.
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Journal ArticleDOI
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.
Satomi Kuramochi-Miyagawa,Tohru Kimura,Takashi W. Ijiri,Taku Isobe,Noriko Asada,Yukiko Fujita,Masahito Ikawa,Naomi Iwai,Masaru Okabe,Wei Deng,Haifan Lin,Yoichi Matsuda,Toru Nakano +12 more
TL;DR: The similarities in the phenotypes of the MILI- and MVH-deficient mice and in the physical binding properties of MILI and MVh indicate a functional association of these proteins in post-transcriptional regulation, and indicate that MILI is essential for the differentiation of spermatocytes.
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Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors
Haruhiko Akiyama,Jung-Eun Kim,Jung-Eun Kim,Kazuhisa Nakashima,Gener Balmes,Naomi Iwai,Jian Min Deng,Zhaoping Zhang,James F. Martin,Richard R. Behringer,Takashi Nakamura,Benoit de Crombrugghe +11 more
TL;DR: The results strongly suggest that all osteo-chondroprogenitor cells, as well as progenitors in a variety of tissues, are derived from Sox9-expressing precursors during mouse embryogenesis.
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Notch signaling regulates left–right asymmetry determination by inducing Nodal expression
Luke T. Krebs,Naomi Iwai,Shigenori Nonaka,Ian C. Welsh,Yu Lan,Rulang Jiang,Yukio Saijoh,Timothy P. O'Brien,Hiroshi Hamada,Thomas Gridley +9 more
TL;DR: It is demonstrated that Dll1-mediated Notch signaling is essential for generation of left- right asymmetry, and that the Notch pathway acts upstream of Nodal expression during left-right asymmetry determination in mice.
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Horizontal Basal Cells Are Multipotent Progenitors in Normal and Injured Adult Olfactory Epithelium
TL;DR: It is shown that even during normal neuronal turnover, HBCs actively generate neuronal and non‐neuronal cells throughout adulthood, and upon selective depletion of mature ORNs by olfactory bulbectomy,HBCs give rise to more neurons.
Journal ArticleDOI
Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos
Aiko Kawasumi,Tetsuya Nakamura,Naomi Iwai,Kenta Yashiro,Yukio Saijoh,José António Belo,José António Belo,Hidetaka Shiratori,Hiroshi Hamada +8 more
TL;DR: The results suggest that LPM is the direct target of Nodal secreted by the perinodal cells, and that an L>R distribution of active Nodals in the node is translated into the asymmetry in LPM.