N
Nardos Lijam
Researcher at National Institutes of Health
Publications - 7
Citations - 1340
Nardos Lijam is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Wnt signaling pathway & Dishevelled. The author has an hindex of 5, co-authored 7 publications receiving 1287 citations. Previous affiliations of Nardos Lijam include Columbus State Community College.
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Journal ArticleDOI
Social Interaction and Sensorimotor Gating Abnormalities in Mice Lacking Dvl1
Nardos Lijam,Richard Paylor,Michael P. McDonald,Jacqueline N. Crawley,Chu-Xia Deng,Karl Herrup,Karen E. Stevens,Gianmaria Maccaferri,Chris J. McBain,Daniel J. Sussman,Anthony Wynshaw-Boris +10 more
TL;DR: Surprisingly, Dvl1-deficient mice exhibited reduced social interaction, including differences in whisker trimming, deficits in nest-building, less huddling contact during home cage sleeping, and subordinate responses in a social dominance test.
Journal ArticleDOI
Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure
Natasha S. Hamblet,Nardos Lijam,Pilar Ruiz-Lozano,Jianbo Wang,Yasheng Yang,Zhenge Luo,Lin Mei,Kenneth R. Chien,Daniel J. Sussman,Anthony Wynshaw-Boris,Anthony Wynshaw-Boris +10 more
TL;DR: Dvl2 is essential for normal cardiac morphogenesis, somite segmentation and neural tube closure, and there is functional redundancy between Dvl1 and Dvl2 in some phenotypes.
Journal ArticleDOI
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development.
S. Leah Etheridge,Saugata Ray,Shuangding Li,Natasha S. Hamblet,Nardos Lijam,Michael Tsang,Joy M. Greer,Natalie Kardos,Jianbo Wang,Daniel J. Sussman,Ping Chen,Anthony Wynshaw-Boris,Anthony Wynshaw-Boris +12 more
TL;DR: It is demonstrated that Dvl3 is required for cardiac outflow tract development and its importance in the PCP pathway during neurulation and cochlea development and several developmental processes in which the three Dvls are functionally redundant are established.
Journal ArticleDOI
Isolation and characterization of mouse dishevelled-3.
Michael Tsang,Nardos Lijam,Yasheng Yang,David R. Beier,Anthony Wynshaw-Boris,Daniel J. Sussman +5 more
TL;DR: Using RT‐PCR with degenerate primers, another member of the mouse Dishevelled (Dvl) gene family is isolated, Dvl3, which maps to mouse chromosome 16 and shares 64 and 62% identity to Dvl1 and Dvl2.
Journal ArticleDOI
Genomic organization of mouse Dishevelled genes.
TL;DR: Two new genomic loci corresponding to the mouse Dishevelled (Dvl) genes Dvl2 and Dvl3 are reported, which are homologs of the Drosophila dsh segment polarity gene and involved in the Wnt/wingless signal transduction pathway.