N
Nicola L. Harris
Researcher at Monash University
Publications - 121
Citations - 10360
Nicola L. Harris is an academic researcher from Monash University. The author has contributed to research in topics: Immune system & Heligmosomoides polygyrus. The author has an hindex of 40, co-authored 110 publications receiving 8780 citations. Previous affiliations of Nicola L. Harris include University of Lausanne & University of Otago.
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A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8+ T cell responses
Stefan Freigang,Bruno Eschli,Nicola L. Harris,Nicola L. Harris,Markus B. Geuking,Katharina Quirin,Sabrina Schrempf,Raphaël M. Zellweger,Jacqueline Weber,Hans Hengartner,Rolf M. Zinkernagel +10 more
TL;DR: Immunization of mice with tumor cells expressing an ER-retained LCMV-GP variant cross-primed protective antiviral cytotoxic T lymphocyte responses in vivo at least 10,000-fold better than immunization with cells expressing the cross-presentation-“resistant” wild-type LCMv-GP.
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The interplay of type 2 immunity, helminth infection and the microbiota in regulating metabolism.
TL;DR: More recent evidence indicating that helminth infection can provide protection against metabolic syndrome is discussed, and the possible contributions of altered nutrient uptake, adipose tissue function and/or the intestinal microbiota with the ability of helminths to alter metabolic status are explored.
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Specific repair by discerning macrophages
TL;DR: The understanding of the plasticity of macrophages is expanded by demonstrating that these cells integrate signals from specific cytokines and from local “organ-specific” cues, or from sensing dying cells, before activating tissue-repair programs.
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Advances in helminth immunology: optimism for future vaccine design?
TL;DR: A combined strategy of drug treatment for the expulsion of adult worms and vaccination designed to halt reinfection would offer the most effective means of control.
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Understanding the role of antibodies in murine infections with Heligmosomoides (polygyrus) bakeri: 35 years ago, now and 35 years ahead
TL;DR: This review reminds readers of the state of knowledge in the 1970s, when the first volume of Parasite Immunology was published, focusing on the role of antibodies in protective immunity, and shows how the understanding of the host–parasite relationship then developed over the following 35 years to date.