N
Nikolaus Rajewsky
Researcher at Max Delbrück Center for Molecular Medicine
Publications - 190
Citations - 59153
Nikolaus Rajewsky is an academic researcher from Max Delbrück Center for Molecular Medicine. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 76, co-authored 164 publications receiving 50045 citations. Previous affiliations of Nikolaus Rajewsky include New York University & Rockefeller University.
Papers
More filters
Journal ArticleDOI
Exact solution of a cellular automaton for traffic
TL;DR: The model studied is the asymmetric exclusion process (ASEP) with simultaneous updating of all sites, equivalent to a special case of the Nagel–Schreckenberg model for highway traffic, which has found many applications in real-time traffic simulations.
Journal ArticleDOI
In vivo and transcriptome-wide identification of RNA binding protein target sites.
Anna-Carina Jungkamp,Marlon Stoeckius,D. Mecenas,Dominic Grün,Guido Mastrobuoni,Stefan Kempa,Nikolaus Rajewsky +6 more
TL;DR: iAR-CLIP is established to determine, at nucleotide resolution, transcriptome-wide binding sites of GLD-1, a conserved, germline-specific translational repressor in C. elegans, and it is proposed that GLd-1 interacts with the translation machinery near the start codon, a so-far-unknown mode of gene regulation in eukaryotes.
Journal ArticleDOI
Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells
Pinar Önal,Dominic Grün,Catherine Adamidi,Agnieszka Rybak,Jordi Solana,Guido Mastrobuoni,Yongbo Wang,Hans-Peter Rahn,Wei Chen,Stefan Kempa,Ulrike Ziebold,Nikolaus Rajewsky +11 more
TL;DR: In this article, the authors analyzed the gene expression in freshwater planaria and found conserved expression of epigenetic regulators and demonstrated their requirement for planarian regeneration by knockdown experiments.
Journal ArticleDOI
Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis
TL;DR: This work used comprehensive and untargeted single-cell RNA profiling to generate a molecular cell atlas of the largest germinal region of the adult mouse brain, the subventricular zone (SVZ), and characterized >20 neural and non-neural cell types.
Journal ArticleDOI
High-resolution profiling and discovery of planarian small RNAs
Marc R. Friedländer,Catherine Adamidi,Ting Han,Svetlana Lebedeva,Thomas A. Isenbarger,Martin Hirst,Marco A. Marra,Chad Nusbaum,William Lee,James C. Jenkin,Alejandro Sánchez Alvarado,John Kim,Nikolaus Rajewsky +12 more
TL;DR: The first comprehensive small RNA analysis in animals belonging to the third animal superphylum, the Lophotrochozoa, is presented, and a number of miRNAs that may function in regeneration are single out.