N
Nikolaus Rajewsky
Researcher at Max Delbrück Center for Molecular Medicine
Publications - 190
Citations - 59153
Nikolaus Rajewsky is an academic researcher from Max Delbrück Center for Molecular Medicine. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 76, co-authored 164 publications receiving 50045 citations. Previous affiliations of Nikolaus Rajewsky include New York University & Rockefeller University.
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Journal ArticleDOI
Expression of Circ_Satb1 Is Decreased in Mesial Temporal Lobe Epilepsy and Regulates Dendritic Spine Morphology
Andreia Gomes-Duarte,Morten T. Venø,Marina de Wit,Ketharini Senthilkumar,Mark H. Broekhoven,Joëlle van den Herik,Fleur R. Heeres,Daniëlle van Rossum,Mateja Rybiczka-Tesulov,Ivano Legnini,Peter C. van Rijen,Pieter van Eijsden,Peter H. Gosselaar,Nikolaus Rajewsky,Jørgen Kjems,Vamshidhar R. Vangoor,R. Jeroen Pasterkamp +16 more
TL;DR: Overall, the results identify a novel epilepsy-associated circRNA with disease-specific expression and previously unidentified cellular effects that are relevant for epileptogenesis.
Posted ContentDOI
Single-cell transcriptomics characterizes cell types in the subventricular zone and uncovers molecular defects underlying impaired adult neurogenesis
TL;DR: Unbiased single-cell RNA profiling is used to generate an unbiased molecular atlas of all cell types in the largest neurogenic niche of the adult mouse brain, the subventricular zone (SVZ), and provides insights into the dynamics of neurogenesis by predicting future cell states based on computational analysis of RNA kinetics.
Journal Article
Decoding the genome- computational identification of microRNA targets
TL;DR: For an Invited Paper for the MAR05 Meeting of The American Physical Society Decoding the genomecomputational identification of microRNA targets NIKOLAUS RAJEWSKY, New York University
Identification of Transcription Factor LIN-15B::GFP Binding Regions in L3
Mb Gerstein,Zj Lu,El Van Nostrand,Chao Cheng,Bi Arshinoff,Tao Liu,Ky Yip,R. Robilotto,Andreas Rechtsteiner,Kohta Ikegami,P. Alves,A. Chateigner,Marc D. Perry,M. Morris,Rk Auerbach,X. Feng,Jing Leng,A. Vielle,Wei Niu,Kahn Rhrissorrakrai,Ashish Agarwal,Rp Alexander,Galt P. Barber,Cm Brdlik,J. Brennan,Jj Brouillet,Adrian Carr,Cheung,Hiram Clawson,Sergio Contrino,Lo Dannenberg,Af Dernburg,Arshad Desai,L. Dick,Ac Dose,Jiang Du,Thea A. Egelhofer,Sevinc Ercan,Ghia Euskirchen,Brent Ewing,Ea Feingold,Reto Gassmann,Pj Good,Philip Green,F. Gullier,M. Gutwein,Guyer,Lukas Habegger,Ting Han,Jg Henikoff,Henz,Angie S. Hinrichs,H. Holster,Tony Hyman,Al Iniguez,J. Janette,M. Jensen,Masaomi Kato,Wj Kent,E. Kephart,Khivansara,Ekta Khurana,Jk Kim,P. Kolasinska-Zwierz,Ec Lai,Isabel J. Latorre,A. Leahey,Suzanna E. Lewis,Paul Lloyd,Lucas Lochovsky,Rf Lowdon,Yaniv Lubling,Rachel Lyne,Michael J. MacCoss,Sd Mackowiak,Marco Mangone,Sheldon J. McKay,D. Mecenas,Gennifer E. Merrihew,Dm Miller,A. Muroyama,Ji Murray,Sl Ooi,H. Pham,T. Phippen,Ea Preston,Nikolaus Rajewsky,Gunnar Rätsch,Heidi Rosenbaum,Joel Rozowsky,Kim Rutherford,P. Ruzanov,Mihail Sarov,Rajkumar Sasidharan,Andrea Sboner,P. Scheid,Eran Segal,Hyunjin Shin,C. Shou,Fj Slack,C. Slightam,Richard J.H. Smith,Wc Spencer,Eo Stinson,S. Taing,Teruaki Takasaki,D. Vafeados,K. Voronina,Guilin Wang,Nl Washington,Cm Whittle,Beijing Wu,Kk Yan,Georg Zeller,Z. Zha,Mei Zhong,X. Zhou,Julie Ahringer,Susan Strome,Kc Gunsalus,Gos Micklem,Xs Liu,Reinke,Sk Kim,Lw Hillier,Steven Henikoff,Fabio Piano,Michael Snyder,Lincoln Stein,Lieb,Rh Waterston,C. Chen,Elicia Preston,C. Slightham,L. Jiang,Aa Hyman,Mark Gerstein +136 more
Journal ArticleDOI
Sites of transcription initiation drive mRNA isoform selection
Carlos Alfonso-Gonzalez,Ivano Legnini,Sarah Holec,Laura Arrigoni,Fernando Mateos,David Koppstein,Agnieszka Rybak-Wolf,Ulrike Bönisch,Nikolaus Rajewsky,Valérie Hilgers +9 more
TL;DR: In this article , the regulatory relationship between transcription initiation, alternative splicing, and 3' end site selection is assessed. But the authors focus on the 3' site of transcription initiation (TSS) and do not consider the impact of TSS choice on the regulation of transcript diversity and tissue identity.