O
Olivier Kocher
Researcher at Beth Israel Deaconess Medical Center
Publications - 100
Citations - 11479
Olivier Kocher is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: PDZ domain & Receptor. The author has an hindex of 47, co-authored 100 publications receiving 10822 citations. Previous affiliations of Olivier Kocher include Yale University & Harvard University.
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Journal ArticleDOI
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
Susumu Kobayashi,Titus J. Boggon,Tajhal Dayaram,Pasi A. Jänne,Olivier Kocher,Matthew Meyerson,Bruce E. Johnson,Michael J. Eck,Daniel G. Tenen,Balazs Halmos,Balazs Halmos +10 more
TL;DR: In this paper, the authors reported the case of a patient with EGFR-mutant, gefitinib-responsive, advanced non-small-cell lung cancer who had a relapse after two years of complete remission.
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Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
Michael Detmar,Lawrence F. Brown,Kevin P. Claffey,Kiang-Teck J. Yeo,Olivier Kocher,Robert W. Jackman,Brygida Berse,Harold F. Dvorak +7 more
TL;DR: It is reported here that the hyperplastic epidermis of psoriatic skin expresses strikingly increased amounts of vascular permeability factor (VPF; vascular endothelial growth factor), a selective endothelial cell mitogen that enhances microvascular permeability.
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Actin expression in smooth muscle cells of rat aortic intimal thickening, human atheromatous plaque, and cultured rat aortic media.
TL;DR: This pattern of actin expression represents a new reliable protein-chemical marker of experimental and human atheromatous smooth muscle cells and is presented as a novel marker of rat and human aortic intimal thickening.
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Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.
Anurag Kumar Singh,Brigitte Riederer,Anja Krabbenhöft,Brigitte Rausch,Janina Bonhagen,Ulrich Lehmann,Hugo R. de Jonge,Mark Donowitz,C. Chris Yun,Edward J. Weinman,Olivier Kocher,Boris M. Hogema,Ursula Seidler +12 more
TL;DR: The data suggest that the NHERF proteins differentially modulate duodenal HCO3- secretion: while NherF1 is an obligatory linker for beta2-AR stimulation of CFTR, NHERf2 confers inhibitory signals by coupling the LPA receptor to CFTR.
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Pulmonary Infiltrates, Eosinophilia, and Cardiomyopathy Following Corticosteroid Withdrawal in Patients With Asthma Receiving Zafirlukast
Michael E. Wechsler,Erik Garpestad,Steven R. Flier,Olivier Kocher,David A. Weiland,Albert J. Polito,Michelle M. Klinek,Timothy D. Bigby,Gordon A. Wong,Richard A. Helmers,Jeffrey M. Drazen +10 more
TL;DR: The clinical syndrome improved with discontinuation of zafirlukast treatment and reinitiation of corticosteroid treatment or addition of cyclophosphamide treatment, and may have resulted from an allergic response to this medication.