O
Olivier Turrini
Researcher at Aix-Marseille University
Publications - 171
Citations - 4731
Olivier Turrini is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Pancreatectomy & Pancreatic cancer. The author has an hindex of 37, co-authored 152 publications receiving 3925 citations. Previous affiliations of Olivier Turrini include Indiana University & French Institute of Health and Medical Research.
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Journal ArticleDOI
Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: A single-institution experience
C. Max Schmidt,Olivier Turrini,Purvi Parikh,Michael G. House,Nicholas J. Zyromski,Atilla Nakeeb,Thomas J. Howard,Henry A. Pitt,Keith D. Lillemoe +8 more
TL;DR: Improve in PD outcomes, including mortality, occurred with increased PD volume at a pancreatic center, and surgeon experience remained an important determinant of overall morbidity.
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Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma
Fabienne Guillaumond,Julie Leca,Orianne Olivares,Marie Noelle Lavaut,Nicolas Vidal,Patrice Berthezene,Nelson Dusetti,Celine Loncle,Ezequiel Calvo,Olivier Turrini,Juan L. Iovanna,Richard Tomasini,Sophie Vasseur +12 more
TL;DR: It is reported that hypoxia increases transcription of hexosamine biosynthetic pathway genes as well as levels of O-glycosylated proteins and that O-linked N-acetylglucosaminylation of proteins is a process required for hypoxic pancreatic cancer cell survival.
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Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes
Gwen Lomberk,Yuna Blum,Rémy Nicolle,Asha Nair,Krutika S. Gaonkar,Laetitia Marisa,Angela Mathison,Zhifu Sun,Huihuang Yan,Nabila Elarouci,Lucile Armenoult,Mira Ayadi,Tamas Ordog,Jeong Heon Lee,Gavin R. Oliver,Eric W. Klee,Vincent Moutardier,Odile Gayet,Benjamin Bian,Pauline Duconseil,Marine Gilabert,Martin Bigonnet,Stéphane Garcia,Olivier Turrini,Jean Robert Delpero,Marc Giovannini,Philippe Grandval,Mohamed Gasmi,Véronique Secq,Aurélien de Reyniès,Nelson Dusetti,Juan L. Iovanna,Raul Urrutia,Raul Urrutia +33 more
TL;DR: Patient-derived PDAC xenografts are utilized to define the epigenomic landscape of PDAC, highlighting chromatin states linked to differing disease aggressiveness and survival and offering potential new markers and therapeutic targets.
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BAYPAN study: a double-blind phase III randomized trial comparing gemcitabine plus sorafenib and gemcitabine plus placebo in patients with advanced pancreatic cancer
A. Goncalves,Marine Gilabert,E. Francois,Laetitia Dahan,Hervé Perrier,R. Lamy,D. Re,Rémy Largillier,Mohamed Gasmi,X. Tchiknavorian,Benjamin Esterni,Dominique Genre,Laurence Moureau-Zabotto,M Giovannini,J.F. Seitz,J. R. Delpero,Olivier Turrini,Olivier Turrini,Patrice Viens,J-L. Raoul +19 more
TL;DR: The addition of sorafenib to gemcitabine does not improve PFS in APC patients and the overall response rates were similar (19 and 23%, respectively).
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Pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: a French multicentre prospective evaluation of resection margins in 150 evaluable specimens
Jean Robert Delpero,Philippe Bachellier,N. Regenet,Yves Patrice Le Treut,François Paye,Nicolas Carrere,Alain Sauvanet,Aurélie Autret,Olivier Turrini,Geneviève Monges-Ranchin,Jean Marie Boher +10 more
TL;DR: Pancreaticoduodenectomy requiring PV-SMVR was associated with a higher risk for R1 resection and the standardization of histopathological analysis has a clinically relevant impact on PFS data.