O
Otto C. Boerman
Researcher at Radboud University Nijmegen
Publications - 358
Citations - 17532
Otto C. Boerman is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Radioimmunotherapy & In vivo. The author has an hindex of 66, co-authored 355 publications receiving 15882 citations. Previous affiliations of Otto C. Boerman include Radboud University Nijmegen Medical Centre.
Papers
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Journal ArticleDOI
Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy
I. Jolanda M. de Vries,W. Joost Lesterhuis,Jelle O. Barentsz,Pauline Verdijk,J. Han van Krieken,Otto C. Boerman,Wim J.G. Oyen,Johannes J. Bonenkamp,Jan B.M. Boezeman,Gosse J. Adema,Jeff W.M. Bulte,Tom W. J. Scheenen,Cornelis J. A. Punt,Arend Heerschap,Carl G. Figdor +14 more
TL;DR: In vivo magnetic resonance tracking of magnetically labeled cells is feasible in humans for detecting very low numbers of dendritic cells in conjunction with detailed anatomical information and appears clinically safe and well suited to monitor cellular therapy in humans.
Journal Article
Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state
I. Jolanda M. de Vries,Daniëlle J. E. B. Krooshoop,Nicole M. Scharenborg,W. Joost Lesterhuis,J. Heleen S. Diepstra,Goos N.P. van Muijen,S. P. Strijk,Theo J.M. Ruers,Otto C. Boerman,Wim J.G. Oyen,Gosse J. Adema,Cornelis J. A. Punt,Carl G. Figdor +12 more
TL;DR: It is demonstrated that in vitro-generated mature, but not immature dendritic cells, efficiently migrate into the T-cell areas of lymph nodes of melanoma patients.
Journal Article
Accelerated Blood Clearance and Altered Biodistribution of Repeated Injections of Sterically Stabilized Liposomes
E.T.M. Dams,Peter Laverman,Wim J.G. Oyen,Gert Storm,Gerrit L. Scherphof,Jos W. M. van der Meer,Frans H.M. Corstens,Otto C. Boerman +7 more
TL;DR: Administration of sterically stabilized PEG liposomes significantly altered the pharmacokinetic behavior of subsequently injected PEGliposomes in a time- and frequency-dependent manner, and the observed phenomenon may have important implications for the repeated administration of sterially stabilized liposome for targeted drug delivery.
Journal ArticleDOI
Peritoneal Carcinomatosis of Colorectal Origin: Incidence and Current Treatment Strategies
TL;DR: Cytoreductive surgery and adjuvant (hyperthermic) IPEC have been shown to be efficacious in selected patients and should therefore be considered in patients with resectable PC of colorectal origin.
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A Novel Method of 18F Radiolabeling for PET
William J. McBride,Robert M. Sharkey,Habibe Karacay,Christopher A. D’Souza,Edmund A. Rossi,Peter Laverman,Chien-Hsing Chang,Otto C. Boerman,David M. Goldenberg +8 more
TL;DR: The ability to bind highly stable Al18F to metal-binding ligands is a promising new labeling method that should be applicable to a diverse array of molecules for PET.