P
Patrice Berthezene
Researcher at French Institute of Health and Medical Research
Publications - 41
Citations - 2473
Patrice Berthezene is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Calcium oxalate & Gene. The author has an hindex of 24, co-authored 41 publications receiving 2236 citations. Previous affiliations of Patrice Berthezene include Necker-Enfants Malades Hospital.
Papers
More filters
Journal ArticleDOI
Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma
Fabienne Guillaumond,Julie Leca,Orianne Olivares,Marie Noelle Lavaut,Nicolas Vidal,Patrice Berthezene,Nelson Dusetti,Celine Loncle,Ezequiel Calvo,Olivier Turrini,Juan L. Iovanna,Richard Tomasini,Sophie Vasseur +12 more
TL;DR: It is reported that hypoxia increases transcription of hexosamine biosynthetic pathway genes as well as levels of O-glycosylated proteins and that O-linked N-acetylglucosaminylation of proteins is a process required for hypoxic pancreatic cancer cell survival.
Journal ArticleDOI
Case‐control study on colorectal cancer and diet in marseilles
G Macquart-Moulin,Elio Riboli,Jacqueline Cornée,Bernadette Charnay,Patrice Berthezene,Nicholas Day +5 more
TL;DR: The intake of several nutrients, particularly vitamins B2, B6, C, potassium, iron, magnesium and vegetable fibre, was lower among cases, however, when all these nutrients were analysed jointly and adjusted one for the other, only potassium retained a significant effect.
Journal ArticleDOI
Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
Orianne Olivares,Jared R. Mayers,Victoire Gouirand,Margaret E. Torrence,Tristan Gicquel,Laurence Borge,Sophie Lac,Julie Roques,Marie-Noëlle Lavaut,Patrice Berthezene,Marion Rubis,Véronique Secq,Stéphane Garcia,Vincent Moutardier,Dominique Lombardo,Juan L. Iovanna,Richard Tomasini,Fabienne Guillaumond,Matthew G. Vander Heiden,Matthew G. Vander Heiden,Sophie Vasseur +20 more
TL;DR: It is demonstrated that collagen serves as a proline reservoir for PDAC cells to use as a nutrient source when other fuels are limited and that proline oxidase (PRODH1) is required forPDAC cell proliferation in vitro and in vivo.
Journal ArticleDOI
Colorectal polyps and diet: a case-control study in Marseilles.
TL;DR: The hypothesis that some components of carbohydrates play a protective role in relation to the biology of tumours of the intestinal tract is considered in further multivariate analyses and in the “Discussion”.
Journal ArticleDOI
Changes in pancreatic exocrine secretion with age: pancreatic exocrine secretion does decrease in the elderly.
TL;DR: One can conclude that pancreatic secretion changes in humans with age, through a decrease in flow rate, bicarbonate and enzyme secretion while calcium concentration is enhanced.