L
Li Zhao
Researcher at Chinese Center for Disease Control and Prevention
Publications - 23
Citations - 3328
Li Zhao is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Antibody & Wafer. The author has an hindex of 9, co-authored 20 publications receiving 2571 citations.
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Journal ArticleDOI
In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Xueting Yao,Fei Ye,Miao Zhang,Cheng Cui,Baoying Huang,Peihua Niu,Xu Liu,Li Zhao,Erdan Dong,Chunli Song,Siyan Zhan,Roujian Lu,Haiyan Li,Wenjie Tan,Dongyang Liu +14 more
TL;DR: It is proposed that the immunomodulatory effect of hydroxychloroquine also may be useful in controlling the cytokine storm that occurs late-phase in critically ill SARS-CoV-2 infected patients.
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Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2.
Hui Wang,Yuntao Zhang,Baoying Huang,Wei Deng,Yaru Quan,Wenling Wang,Wenbo Xu,Yuxiu Zhao,Na Li,Jin Zhang,Hongyang Liang,Linlin Bao,Yanfeng Xu,Ling Ding,Weimin Zhou,Hong Gao,Jiangning Liu,Peihua Niu,Li Zhao,Wei Zhen,Hui Fu,Yu Shouzhi,Zhang Zhengli,Guangxue Xu,Changgui Li,Zhiyong Lou,Miao Xu,Chuan Qin,Guizhen Wu,George F. Gao,Wenjie Tan,Xiaoming Yang +31 more
TL;DR: Two-dose immunizations using 2 μg/dose of BBIBP-CorV provided highly efficient protection against SARS-CoV-2 intratracheal challenge in rhesus macaques, without detectable antibody-dependent enhancement of infection.
Journal ArticleDOI
Age-related rhesus macaque models of COVID-19
Pin Yu,Feifei Qi,Yanfeng Xu,Fengdi Li,Peipei Liu,Jiayi Liu,Linlin Bao,Wei Deng,Hong Gao,Zhiguang Xiang,Chong Xiao,Qi Lv,Shuran Gong,Jiangning Liu,Zhiqi Song,Yajin Qu,Jing Xue,Qiang Wei,Mingya Liu,Guanpeng Wang,Shunyi Wang,Haisheng Yu,Xing Liu,Baoying Huang,Wenling Wang,Li Zhao,Huijuan Wang,Fei Ye,Weimin Zhou,Wei Zhen,Jun Han,Guizhen Wu,Qi Jin,Jianwei Wang,Wenjie Tan,Chuan Qin +35 more
TL;DR: Since December 2019, an outbreak of the Corona Virus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) in Wuhan, China, has become a public health emergency of international concern.
Journal ArticleDOI
SARS-CoV-2-Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19.
Chen Chen,Guiju Gao,Yanli Xu,Lin Pu,Qi Wang,Liming Wang,Wenling Wang,Yangzi Song,Meiling Chen,Linghang Wang,Fengting Yu,Siyuan Yang,Yunxia Tang,Li Zhao,Huijuan Wang,Yajie Wang,Hui Zeng,Fujie Zhang +17 more
TL;DR: A convenience sample of patients admitted to Beijing Ditan Hospital, Capital Medical University, with a diagnosis of COVID-19 and paired RT-qPCR testing of pharyngeal swabs with either sputum or feces samples showed positive results for SARS–CoV-2 RNA.
Journal ArticleDOI
Non-invasive bioluminescence imaging of HCoV-OC43 infection and therapy in the central nervous system of live mice.
Junwei Niu,Shen Liang,Baoying Huang,Fei Ye,Li Zhao,Huijuan Wang,Yao Deng,Wenjie Tan,Wenjie Tan +8 more
TL;DR: These results provide new insights into the temporal and spatial dissemination of HCoV-OC43 in the CNS, and the methods provide an extremely sensitive platform for evaluating the efficacy of antiviral therapies to treat neuroinvasive HCoVs in live mice.