Showing papers in "Trends in Biotechnology in 2009"

TL;DR: This classification of the different platelet concentrates into four categories, depending on their leucocyte and fibrin content, should help to elucidate successes and failures that have occurred so far, as well as providing an objective approach for the further development of these techniques.

TL;DR: This review outlines some important areas such as the large-scale development of molecular markers for linkage mapping, association mapping, wide crosses and alien introgression, epigenetic modifications, transcript profiling, population genetics and de novo genome/organellar genome assembly for which these technologies are expected to advance crop genetics and breeding, leading to crop improvement.

TL;DR: This review is intended to summarize the applications of nanotechnology relevant to food and nutraceuticals together with identifying the outstanding challenges.

TL;DR: This work focuses on fermentative hydrogen production and highlights some recently applied approaches, such as response surface methodology, different reactor configurations and organisms that have been used to maximize hydrogen production rates and yields.

TL;DR: Because many bacteria show a natural capacity to cope with contaminants, they could be exploited to improve the efficiency of phytoremediation or to protect the food chain by reducing levels of agrochemicals in food crops.

TL;DR: The current understanding of the process by which N(2)O is produced and destroyed is reviewed and the potential for feeding this into new approaches for combating N( 2)O release is discussed.

TL;DR: The requirements for identifying additional specific growth Factors and evaluating the optimal combination of cells, growth factors and scaffolds that is able to respond to the functional demand placed upon cartilage tissue replacement in clinics are discussed.

TL;DR: This work considers modern usage of fungicides and plant defence activators, assess the usefulness of biological control and categorize current approaches towards blast-tolerant genetically modified rice.

TL;DR: Significant advances in the identification of nucleic acid markers and other novel biomarkers and the development of sensor-based platforms have taken place and these novel strategies have shown promise, and their advantages over the conventional tests are discussed.

TL;DR: Comparison analysis of transducer sensitivity, robustness and susceptibility to interferences are provided and strategies for sensitivity enhancement by means of signal amplification are covered.

TL;DR: This work surveys diatom nanotechnology since 2005, emphasizing recent advances in diatom biomineralization, biophotonics, photoluminescence, microfluidics, compustat domestication, multiscale porosity, silica sequestering of proteins, detection of trace gases, controlled drug delivery and computer design.

TL;DR: It is concluded that although several QbD concepts are being practiced by the biotechnology industry, successful dialogue and partnership between the industry and its regulators will be the key to successfulQbD implementation.

TL;DR: This review summarizes the current state of the art in areas where sonochemistry could be successfully combined with biotechnology with the aim of enhancing the efficiency of bioprocesses, including biofuel production, biop rocess monitoring, enzyme biocatalysts, biosensors and biosludge treatment.

TL;DR: This work focuses on the paracrine signals secreted by both cell types and the effects they elicit, and discusses the other modes of cell-to-cell communication that could explain their cell coupling and reciprocal interactions.

TL;DR: The principles and utilities of magnetically enhanced transfection, magnetically assisted gene therapy, magnetic induced hyperthermia and magnetic-force-based tissue engineering, and the principles and Utilities of these applications will be discussed here.

TL;DR: Nanoobiotechnology is becoming a commercially feasible and promising opportunity for oral, pulmonary and transdermal administration routes and there is a drive in the biotechnology industry to produce needle-free and more user-friendly drugs.

TL;DR: This review highlights the potential of methylotrophic bacteria for the development of economically competitive bioprocesses based on methanol as an alternative carbon source, bringing together biological, technical and economic considerations.

TL;DR: This emerging and multidisciplinary approach offers new opportunities for the design and control of stem cells in tissue engineering and cellular therapies and promises to expedite drug discovery in the biotechnology and pharmaceutical industries.

TL;DR: This review highlights the milestones in the development of metabolically engineered production strains that possess a high degree of catabolic versatility and are homoethanologenic, with particular focus on theDevelopment of reliable methods for cell competency, gene deletion or upregulation.

TL;DR: The factors affecting bioanode performance, the recent advances and the prospective strategies for improving it are reviewed and future application perspectives of bioanodes are proposed.

TL;DR: Self-assembling peptide-based biomaterials are being developed for use as 3D tissue engineering scaffolds and for therapeutic drug-release applications and microbes, particularly safe organisms used in the food industry, offer a more rapid route to the large-scale production.

TL;DR: Aqueous two-phase extraction is a potential and promising liquid-liquid extraction technique for the purification of biomolecules that combines a high selectivity and biocompatibility with an easy scale-up and continuous operation mode.

TL;DR: A variety of biofilm reactor configurations have been explored for productive catalysis and some reactors have been operated continuously for months, which all facilitate continuous processing.

TL;DR: This review addresses the physical principles associated with the QCM, as well as the origin and effects of major interfering phenomena, and special attention is paid to the possibilities offered by QCM that go beyond microweighing.

TL;DR: The potential and current limitations in exploiting the immunomodulatory activity of IDRs as a novel anti-infective pathway are discussed.

TL;DR: This review will focus on several recently discovered compounds, primarily from cyanobacteria and actinobacteria, that illustrate the tremendous potential of marine bacteria as a source of new therapeutics within the areas of oncology and infectious diseases.

TL;DR: The precipitation of biogenic manganese and iron species and the microbial reduction of precious metals, such as palladium, platinum, silver and gold, are discussed with specific attention to the application of these biogenic metals in innovative remediation technologies in advanced water treatment.

TL;DR: How nanopore probe techniques will provide a new generation of research tools in nanomedicine for quantitatively examining the details of complex recognition and will represent a crucial step in designing other pore-based nanostructures and high-throughput devices for molecular biomedical diagnosis is discussed.

TL;DR: It is likely that the new generation of polymeric HVs will find successful long-term clinical applications in future, as advances in polymers, nanomaterials and surface modification techniques have resulted in improved biocompatibility and biostability.

TL;DR: Different available methods of trans-resveratrol production through recombinant microorganisms and plant cell suspensions are described and compared, with a focus on their respective advantages, limits and perspectives as a basis for scale-up in large culture volumes.