P
Peter T. Nelson
Researcher at University of Kentucky
Publications - 305
Citations - 28872
Peter T. Nelson is an academic researcher from University of Kentucky. The author has contributed to research in topics: Dementia & Alzheimer's disease. The author has an hindex of 71, co-authored 266 publications receiving 23763 citations. Previous affiliations of Peter T. Nelson include Fred Hutchinson Cancer Research Center & Pennsylvania State University.
Papers
More filters
Journal ArticleDOI
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
Bradley T. Hyman,Creighton H. Phelps,Thomas G. Beach,Eileen H. Bigio,Nigel J. Cairns,Maria C. Carrillo,Dennis W. Dickson,Charles Duyckaerts,Matthew P. Frosch,Eliezer Masliah,Suzanne S. Mirra,Peter T. Nelson,Julie A. Schneider,Dietmar Rudolf Thal,Bill Thies,John Q. Trojanowski,Harry V. Vinters,Thomas J. Montine +17 more
TL;DR: The new guidelines recognize the pre‐clinical stage of AD, enhance the assessment of AD to include amyloid accumulation as well as neurofibrillary change and neuritic plaques, and establish protocols for the neuropathologic assessment of Lewy body disease, vascular brain injury, hippocampal sclerosis, and TDP‐43 inclusions.
Journal ArticleDOI
National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach
Thomas J. Montine,Creighton H. Phelps,Thomas G. Beach,Eileen H. Bigio,Nigel J. Cairns,Dennis W. Dickson,Charles Duyckaerts,Matthew P. Frosch,Eliezer Masliah,Suzanne S. Mirra,Peter T. Nelson,Julie A. Schneider,Dietmar Rudolf Thal,John Q. Trojanowski,Harry V. Vinters,Bradley T. Hyman +15 more
TL;DR: A practical guide for the implementation of recently revised National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer’s disease is presented.
Journal ArticleDOI
Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
Peter T. Nelson,Irina Alafuzoff,Eileen H. Bigio,Constantin Bouras,Heiko Braak,Nigel J. Cairns,Rudolph J. Castellani,Barbara J. Crain,Peter Davies,Kelly Del Tredici,Charles Duyckaerts,Matthew P. Frosch,Vahram Haroutunian,Patrick R. Hof,Christine M. Hulette,Bradley T. Hyman,Takeshi Iwatsubo,Kurt A. Jellinger,Gregory A. Jicha,Eniko Veronika Kovari,Walter A. Kukull,James B. Leverenz,Seth Love,Seth Love,Ian R. A. Mackenzie,David M. A. Mann,Eliezer Masliah,Ann C. McKee,Thomas J. Montine,John C. Morris,Julie A. Schneider,Joshua A. Sonnen,Dietmar Rudolf Thal,John Q. Trojanowski,Juan C. Troncoso,Thomas Wisniewski,Randall L. Woltjer,Thomas G. Beach +37 more
TL;DR: Evidence from many independent research centers strongly supports the existence of a specific disease, as defined by the presence of A&bgr; plaques and neurofibrillary tangles.
Journal ArticleDOI
Primary age-related tauopathy (PART): a common pathology associated with human aging
John F. Crary,John Q. Trojanowski,Julie A. Schneider,Jose F. Abisambra,Erin L. Abner,Irina Alafuzoff,Steven E. Arnold,Johannes Attems,Thomas G. Beach,Eileen H. Bigio,Nigel J. Cairns,Dennis W. Dickson,Marla Gearing,Lea T. Grinberg,Lea T. Grinberg,Patrick R. Hof,Bradley T. Hyman,Kurt A. Jellinger,Gregory A. Jicha,Gabor G. Kovacs,David S. Knopman,Julia Kofler,Walter A. Kukull,Ian R. A. Mackenzie,Eliezer Masliah,Ann C. McKee,Thomas J. Montine,Melissa E. Murray,Janna H. Neltner,Ismael Santa-Maria,William W. Seeley,Alberto Serrano-Pozo,Michael L. Shelanski,Thor D. Stein,Masaki Takao,Dietmar Rudolf Thal,Jonathan B. Toledo,Juan C. Troncoso,Jean Paul G. Vonsattel,Charles L. White,Thomas Wisniewski,Randall L. Woltjer,Masahito Yamada,Peter T. Nelson +43 more
TL;DR: A new term is recommended, “primary age-related tauopathy” (PART), to describe a pathology that is commonly observed in the brains of aged individuals, yet this pathological process cannot be specifically identified pre-mortem at the present time.
Journal ArticleDOI
A combined computational-experimental approach predicts human microRNA targets
Marianthi Kiriakidou,Peter T. Nelson,Andrei Kouranov,Petko Fitziev,Costas Bouyioukos,Zissimos Mourelatos,Artemis G. Hatzigeorgiou +6 more
TL;DR: A computational program is described, "DIANA-microT", that identifies mRNA targets for animal miRNAs and predicts mRNA targets, bearing single MREs, for human and mouse miRN as well as important rules governing miRNA-MRE recognition that allow prediction of human miRNA targets.