Peter W. Gething

TL;DR: Evidence is provided that health system performance, drug quality and patient adherence influence the effectiveness of anti-malarials used in treating uncomplicated falciparum malaria, and this study provides guidance to countries’ treatment practises.

TL;DR: Monthly health facility data can be used to establish seasonal patterns in malaria burden and augment the information provided by household prevalence surveys, and model estimates indicate that while most parts of Madagascar experience peaks in malaria transmission near March–April, the eastern coast experiences an earlier peak around February.

TL;DR: Adding RTS,S to routine malaria control interventions would be highly cost-effective, conditional on assumptions on price, coverage, and vaccine properties, which have the potential to substantially reduce malaria burden in children across Africa.

TL;DR: This work describes the use of a laboratory population model to assess how individual antimalarial drugs can impact the number of secondary Plasmodium berghei infections over a cycle of transmission and calculates effect size for each treatment, allowing for head-to-head comparison of the potential impact of individual drugs within epidemiologically relevant settings.