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Philippe J Guerin
Researcher at University of Oxford
Publications - 248
Citations - 15799
Philippe J Guerin is an academic researcher from University of Oxford. The author has contributed to research in topics: Malaria & Population. The author has an hindex of 52, co-authored 225 publications receiving 13288 citations. Previous affiliations of Philippe J Guerin include Médecins Sans Frontières & EHESP.
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Journal ArticleDOI
Artemether-lumefantrine and dihydroartemisinin-piperaquine exert inverse selective pressure on Plasmodium falciparum drug sensitivity associated haplotypes in Uganda
Aimee R. Taylor,Jennifer A. Flegg,Jennifer A. Flegg,Christopher Holmes,Philippe J Guerin,Carol Hopkins Sibley,Carol Hopkins Sibley,Melissa D. Conrad,Grant Dorsey,Philip J. Rosenthal +9 more
TL;DR: Inverse selective pressure of AL and DP on the complementary haplotypes NFD and YYY suggests that rotating artemisinin-based antimalarial combination regimens may be the best treatment option to prevent resistance selection.
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Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Africa, 1980–2015
Jeanne Elven,Prabin Dahal,Elizabeth A. Ashley,Elizabeth A. Ashley,Nigel V. Thomas,Poojan Shrestha,Kasia Stepniewska,John A. Crump,Paul N. Newton,Derek Bell,Hugh Reyburn,Heidi Hopkins,Philippe J Guerin +12 more
TL;DR: The availability of reliable point-of-care tests for malaria has heralded a paradigm shift in the management of febrile illnesses away from presumptive antimalarial therapy, but better understanding is needed of the true causative agents and their geographic variability.
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The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt 76T: a meta-analysis of individual patient data
Michael T. Bretscher,Prabin Dahal,Jamie T. Griffin,Kasia Stepniewska,Quique Bassat,Elisabeth Baudin,Umberto D'Alessandro,Abdoulaye Djimde,Grant Dorsey,Emmanuelle Espie,Bakary Fofana,Raquel González,Raquel González,Elizabeth Juma,Corine Karema,Corine Karema,Estrella Lasry,Bertrand Lell,Nines Lima,Clara Menéndez,Clara Menéndez,Ghyslain Mombo-Ngoma,Ghyslain Mombo-Ngoma,Clarissa Moreira,Frederic Nikiema,Jean-Bosco Ouédraogo,Sarah G. Staedke,Halidou Tinto,Innocent Valea,Adoke Yeka,Azra C. Ghani,Philippe J Guerin,Lucy C Okell +32 more
TL;DR: Differences in the duration of protection between the artemisinin combination therapies could alter population-level clinical incidence of malaria by up to 14% in under-5-year-old children when the drugs were used as first-line treatments in areas with high, seasonal transmission.
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Performance of a Histidine-Rich Protein 2 Rapid Diagnostic Test, Paracheck Pf®, for Detection of Malaria Infections in Ugandan Pregnant Women
Mehul Dhorda,Patrice Piola,Dan Nyehangane,Benon Tumwebaze,Aisha Nalusaji,Carolyn Nabasumba,Eleanor Turyakira,Rose McGready,Elizabeth A. Ashley,Philippe J Guerin,Georges Snounou +10 more
TL;DR: The RDTs could replace blood smears for diagnosis of malaria in pregnancy by virtue of their relative ease of use and field-based sensitive tests for malaria inregnancy are urgently needed.
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Prevalence, risk factors, and impact on outcome of cytomegalovirus replication in serum of Cambodian HIV-infected patients (2004-2007).
Romain Micol,Philippe Buchy,Gilles Guerrier,Veasna Duong,Laurent Ferradini,Jean-Philippe Dousset,Philippe J Guerin,Suna Balkan,Julie Galimand,Hak Chanroeun,Olivier Lortholary,Christine Rouzioux,Arnaud Fontanet,Marianne Leruez-Ville +13 more
TL;DR: Serum CMV replication is highly prevalent among HIV-infected Cambodian patients and is associated with increased mortality, which underscores the importance of diagnostic CMV infection by PCR in sera of HIV- Infected patients with CD4+ count <100/mm3 and treating this opportunistic infection to reduce its associated mortality.