P
Philippe J Guerin
Researcher at University of Oxford
Publications - 248
Citations - 15799
Philippe J Guerin is an academic researcher from University of Oxford. The author has contributed to research in topics: Malaria & Population. The author has an hindex of 52, co-authored 225 publications receiving 13288 citations. Previous affiliations of Philippe J Guerin include Médecins Sans Frontières & EHESP.
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Journal ArticleDOI
The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis
Robert J. Commons,Julie A. Simpson,Kamala Thriemer,Tesfay Abreha,Ishag Adam,Nicholas M. Anstey,Ashenafi Assefa,Ghulam Rahim Awab,Ghulam Rahim Awab,J. Kevin Baird,Bridget E. Barber,Cindy S. Chu,Prabin Dahal,André Daher,André Daher,Timothy M. E. Davis,Arjen M. Dondorp,Matthew J. Grigg,Georgina S Humphreys,Jimee Hwang,Jimee Hwang,Harin Karunajeewa,Moses Laman,Moses Laman,Kartini Lidia,Brioni R. Moore,Brioni R. Moore,Brioni R. Moore,Ivo Mueller,Ivo Mueller,Ivo Mueller,François Nosten,Ayodhia Pitaloka Pasaribu,Ayodhia Pitaloka Pasaribu,Dhelio Batista Pereira,Aung Pyae Phyo,Jeanne Rini Poespoprodjo,Carol Hopkins Sibley,Kasia Stepniewska,Inge Sutanto,Guy E. Thwaites,Tran Tinh Hien,Nicholas J. White,Timothy William,Charles J. Woodrow,Philippe J Guerin,Ric N. Price +46 more
TL;DR: The risk of recurrent P. vivax recurrence at day 42 is observed to be significantly lower following treatment with DP compared with AL, reflecting the longer period of post-treatment prophylaxis; this risk was reduced substantially by coadministration with PQ.
Journal ArticleDOI
Population pharmacokinetics of Artemether and dihydroartemisinin in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda
Joel Tarning,Frank Kloprogge,Frank Kloprogge,Patrice Piola,Mehul Dhorda,Sulaiman Muwanga,Eleanor Turyakira,Nitra Nuengchamnong,François Nosten,François Nosten,Nicholas P. J. Day,Nicholas P. J. Day,Nicholas J. White,Nicholas J. White,Philippe J Guerin,Niklas Lindegardh,Niklas Lindegardh +16 more
TL;DR: The population pharmacokinetic properties of artemether and dihydroartemisinin, in pregnant women with uncomplicated P. falciparum malaria in Uganda, were described satisfactorily by a simultaneous drug-metabolic model without covariates.
Journal ArticleDOI
Combating poor-quality anti-malarial medicines: a call to action.
TL;DR: It is vital that all stakeholders involved in efforts against poor-quality anti-malarial medicines extend and strengthen their actions in these critical areas and thus effectively support global health development and malaria elimination programmes.
Journal ArticleDOI
Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis
Salim Abdulla,Elizabeth A. Ashley,Quique Bassat,Delia Bethell,Anders Björkman,Steffen Borrmann,Umberto D'Alessandro,Prabin Dahal,Nicholas P. J. Day,Mahamadou Diakite,Abdoulaye Djimde,Arjen M. Dondorp,Socheat Duong,Michael D. Edstein,Rick M. Fairhurst,M. Abul Faiz,Catherine O. Falade,Jennifer A. Flegg,Carole Fogg,Raquel González,Brian Greenwood,Philippe J Guerin,Jean-Paul Guthmann,Kamal Hamed,Tran Tinh Hien,Ye Htut,Elizabeth Juma,Pharath Lim,Andreas Mårtensson,Mayfong Mayxay,Olugbenga A. Mokuolu,Clarissa Moreira,Paul N. Newton,Harald Noedl,François Nosten,Bernhards Ogutu,Marie A. Onyamboko,Seth Owusu-Agyei,Aung Pyae Phyo,Zul Premji,Ric N. Price,Sasithon Pukrittayakamee,Michael Ramharter,Issaka Sagara,Youry Se,Seila Suon,Kasia Stepniewska,Stephen A. Ward,Nicholas J. White,P. A. Winstanley +49 more
TL;DR: In western Cambodia, the region with the highest prevalence of artemisinin resistance, there was no evidence for increasing PC1/2 since 2007 and the relationships between parasite clearance and risk of recrudescence during follow-up were assessed.
Journal ArticleDOI
Complex interactions between malaria and malnutrition: a systematic literature review
Debashish Das,Rebecca F. Grais,Emelda A. Okiro,Kasia Stepniewska,Rashid Mansoor,S van der Kam,Dianne J. Terlouw,Dianne J. Terlouw,Dianne J. Terlouw,Joel Tarning,Joel Tarning,Karen I. Barnes,Philippe J Guerin +12 more
TL;DR: The evidence on the effect of malnutrition on malaria risk remains inconclusive and the need to improve the understanding of the pharmacodynamics and pharmacokinetics of ACTs in malnourished children is highlighted.