P
Ping Jiang
Researcher at Myriad Genetics
Publications - 8
Citations - 1452
Ping Jiang is an academic researcher from Myriad Genetics. The author has contributed to research in topics: Gene & Genetic enhancement. The author has an hindex of 6, co-authored 8 publications receiving 1423 citations.
Papers
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Journal ArticleDOI
The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds.
Sean V. Tavtigian,Jacques Simard,Johanna M. Rommens,Fergus J. Couch,Donna M Shattuck-Eidens,Susan L. Neuhausen,Sofia D. Merajver,Steinunn Thorlacius,Kenneth Offit,Dominique Stoppa-Lyonnet,Carole Bélanger,Russell Bell,Simin Berry,Robert Bogden,Qian Chen,Thaylon Davis,Martine Dumont,Cheryl Frye,T. Hattier,Srikanth Jammulapati,Teresa Janecki,Ping Jiang,Robert Kehrer,J.-F. Leblanc,J.T. Mitchell,Jodi Mcarthur-Morrison,K. Nguyen,Yi Peng,Chantal Samson,Marianne Schroeder,S.C. Snyder,Linda Steele,M. Stringfellow,C. Stroup,Bradley D. Swedlund,J. Swense,David H. F. Teng,Alun Thomas,T.D. Tran,Martine Tranchant,Jane Weaver-Feldhaus,Alexander K. C. Wong,Hiroaki Shizuya,Jorunn E. Eyfjord,Lisa A. Cannon-Albright,Fernand Labrie,Mark H. Skolnick,Mark H. Skolnick,Barbara L. Weber,Alexander Kamb,David E. Goldgar,David E. Goldgar +51 more
TL;DR: The complete coding sequence and exonic structure of BRCA2 is determined, and its pattern of expression is examined, and a mutational analysis of B RCA2 in families selected on the basis of linkage analysis and/or the presence of one or more cases of male breast cancer is reported.
Journal Article
Complex Structure and Regulation of the P16 (MTS1) Locus
Steven Stone,Ping Jiang,Priya Dayananth,Sean V. Tavtigian,Harold Katcher,David Parry,Gordon Peters,Alexander Kamb +7 more
TL;DR: Two transcripts derived from the p16 gene with distinct protein coding potentials are described, and transcription from one of the promoters appears to be regulated, at least in part, by the retinoblastoma gene product.
Journal Article
Genomic structure, expression and mutational analysis of the P15 (MTS2) gene.
Steven Stone,Priya Dayananth,Ping Jiang,Jane Weaver-Feldhaus,Sean V. Tavtigian,Lisa A. Cannon-Albright,Alexander Kamb +6 more
TL;DR: It is shown that ectopic expression of p15 inhibits growth of tumor-derived cell lines and a role for p15 in growth regulation, but a limited role in tumor progression is suggested.
Journal ArticleDOI
Generation of an Integrated Transcription Map of the BRCA2 Region on Chromosome 13q12–q13
Fergus J. Couch,Johanna M. Rommens,Susan L. Neuhausen,Carole Bélanger,Martine Dumont,Kenneth J. Abel,Russell Bell,Simon Berry,Robert Bogden,Lisa A. Cannon-Albright,Linda M. Farid,Cheryl Frye,T. Hattier,Teresa Janecki,Ping Jiang,Robert Kehrer,Jean Francois Leblanc,Jodi Mcarthur-Morrison,David McSweeney,Yoshio Miki,Yi Peng,Carolle Samson,Marianne Schroeder,Sarah C. Snyder,Michael Stringfellow,Carrie Stroup,Brad Swedlund,Jeff Swensen,David H.-R Teng,Sanjay Thakur,Thanh Tran,Martine Tranchant,Jane Welver-Feldhaus,Alexander K. C. Wong,Hiroake Shizuya,Fernand Labrie,Mark H. Skolnick,Mark H. Skolnick,David E. Goldgar,David E. Goldgar,Alexander Kamb,Barbara L. Weber,Sean V. Tavtigian,Jacques Simard +43 more
TL;DR: An integrated approach involving physical mapping, identification of transcribed sequences, and computational analysis of genomic sequence was used to generate a detailed transcription map of the 1.
Patent
Method for ligating adaptors to nucleic acids which methods are useful for obtaining the ends of genes
TL;DR: In this article, the 5' end of the gene is conserved by preparing a first strand of cDNA and ligating to this an adaptor which is partially double stranded wherein the overhang or single stranded region of the adaptor is degenerate.