Q
Qian Cong
Researcher at University of Texas Southwestern Medical Center
Publications - 96
Citations - 5027
Qian Cong is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 20, co-authored 67 publications receiving 2203 citations. Previous affiliations of Qian Cong include University of Washington.
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Journal ArticleDOI
Accurate prediction of protein structures and interactions using a three-track neural network
Minkyung Baek,Frank DiMaio,Ivan Anishchenko,Justas Dauparas,Sergey Ovchinnikov,Gyu Rie Lee,Jue Wang,Qian Cong,Lisa N. Kinch,R. Dustin Schaeffer,Claudia Millán,Hahnbeom Park,Carson Adams,Caleb R. Glassman,Andy DeGiovanni,Jose Henrique Pereira,Andria V. Rodrigues,Alberdina A. van Dijk,Ana C. Ebrecht,Diederik J. Opperman,Theo Sagmeister,Christoph Buhlheller,Christoph Buhlheller,Tea Pavkov-Keller,Manoj K. Rathinaswamy,Udit Dalwadi,Calvin K. Yip,John E. Burke,K. Christopher Garcia,Nick V. Grishin,Paul D. Adams,Paul D. Adams,Randy J. Read,David Baker +33 more
TL;DR: In this article, a three-track network is proposed to combine information at the one-dimensional (1D) sequence level, the 2D distance map level, and the 3D coordinate level.
Journal ArticleDOI
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
Siqi Liu,Xin Cai,Jiaxi Wu,Qian Cong,Xiang Chen,Tuo Li,Fenghe Du,Junyao Ren,You Tong Wu,Nick V. Grishin,Zhijian J. Chen +10 more
TL;DR: A common signaling mechanism used by all three types of innate immune receptor-adaptor protein pairs to activate IRF3 and generate IFNs is reported, which is important because cells must regulate their IFN production carefully to avoid inflammation and autoimmunity.
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Computed structures of core eukaryotic protein complexes.
Ian R. Humphreys,Jimin Pei,Minkyung Baek,Aditya Krishnakumar,Ivan Anishchenko,Sergey Ovchinnikov,Jing Zhang,Travis J. Ness,Sudeep Banjade,Saket R. Bagde,Viktoriya G. Stancheva,Xiao-Han Li,Kaixian Liu,Zhi Zheng,Zhi Zheng,Daniel J. Barrero,Upasana Roy,Jochen Kuper,Israel S. Fernández,Barnabas Szakal,Dana Branzei,Josep Rizo,Caroline Kisker,Eric C. Greene,Sue Biggins,Scott Keeney,Scott Keeney,Elizabeth A. Miller,J. Christopher Fromme,Tamara L. Hendrickson,Qian Cong,David Baker +31 more
TL;DR: The structures of many eukaryotic protein complexes are unknown, and there are likely many protein-protein interactions not yet identified as mentioned in this paper, but these structures play critical roles in biology.
Journal ArticleDOI
Protein interaction networks revealed by proteome coevolution.
TL;DR: A computational approach reveals hundreds of previously uncharacterized PPIs in E. coli and M. tuberculosis that both add components to known protein complexes and networks and establish the existence of new ones.
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CASP9 assessment of free modeling target predictions.
TL;DR: An overview of the ninth round of Critical Assessment of Protein Structure Prediction (CASP9) “Template free modeling” category (FM) is presented, highlighting a trend for human experts to act as “meta predictors” by correctly selecting among models produced by the top‐performing automated servers.