R
R. Veerhuis
Researcher at VU University Medical Center
Publications - 32
Citations - 6346
R. Veerhuis is an academic researcher from VU University Medical Center. The author has contributed to research in topics: Neuroinflammation & Microglia. The author has an hindex of 18, co-authored 28 publications receiving 5807 citations.
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Journal ArticleDOI
Inflammation and Alzheimer's disease.
Haruhiko Akiyama,Steven W. Barger,Scott R. Barnum,B Bradt,Jürgen Bauer,Greg M. Cole,Neil R. Cooper,Piet Eikelenboom,Mark R. Emmerling,Bernd L. Fiebich,Caleb E. Finch,Sally A. Frautschy,W. S. T. Griffin,Harald Hampel,Michael Hüll,Gary E. Landreth,Lih-Fen Lue,Robert E. Mrak,Ian R. A. Mackenzie,Patrick L. McGeer,M K O'Banion,Joel S. Pachter,Giulio Maria Pasinetti,C Plata-Salaman,Joseph G. Rogers,Russell E. Rydel,Yueyang Shen,Wolfgang J. Streit,Ronald Strohmeyer,I Tooyoma,F L van Muiswinkel,R. Veerhuis,David G. Walker,Scott D. Webster,Beatrice Hauss–Wegrzyniak,Gary L. Wenk,Tony Wyss-Coray +36 more
TL;DR: By better understanding AD inflammatory and immunoregulatory processes, it should be possible to develop anti-inflammatory approaches that may not cure AD but will likely help slow the progression or delay the onset of this devastating disorder.
Journal ArticleDOI
The unfolded protein response is activated in Alzheimer's disease.
Jeroen J.M. Hoozemans,R. Veerhuis,E S van Haastert,J. M. Rozemuller,Frank Baas,Piet Eikelenboom,Piet Eikelenboom,Wiep Scheper +7 more
TL;DR: Data show that the UPR is activated in AD, and the increased occurrence of BiP/GRP78 and p-PERK in cytologically normal-appearing neurons suggest a role for the U PR early in AD neurodegeneration.
Journal ArticleDOI
Neuroinflammation – An Early Event in Both the History and Pathogenesis of Alzheimer’s Disease
Piet Eikelenboom,Erik van Exel,Jeroen J.M. Hoozemans,R. Veerhuis,Annemieke J.M. Rozemuller,Willem A. van Gool +5 more
TL;DR: Neuropathological studies show that a neuroinflammatory response in the cerebral neocortex parallels the early stages of AD pathology and precedes the late stage, tau-related pathology, which indicates that systemic markers of the innate immunity are risk factors for late-onset AD.
Journal ArticleDOI
Decreased lysophosphatidylcholine/phosphatidylcholine ratio in cerebrospinal fluid in Alzheimer's disease.
Cjj Mulder,L-O Wahlund,Tom Teerlink,Mari Blomberg,R. Veerhuis,G. J. van Kamp,Ph. Scheltens,Peter G. Scheffer +7 more
TL;DR: The lower lyso-PC/PC ratio in CSF of patients with AD may reflect alterations in the metabolism of choline-containing phospholipids in the brain in AD, and suggests that PC species containing linoleic acid or arachidonic acid are equally involved.
Journal ArticleDOI
Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology
TL;DR: The initial stages of Alzheimer's disease pathology in the neocortex show upregulation of cell cycle proteins, adhesion and inflammation related factors, indicating the early involvement of inflammatory and regenerating pathways in dementia pathogenesis.