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Raffaele Iorio

Researcher at Catholic University of the Sacred Heart

Publications -  192
Citations -  4661

Raffaele Iorio is an academic researcher from Catholic University of the Sacred Heart. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 32, co-authored 157 publications receiving 3689 citations. Previous affiliations of Raffaele Iorio include Sapienza University of Rome & Mayo Clinic.

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Journal ArticleDOI

Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

James F. Howard, +623 more
- 01 Dec 2017 - 
TL;DR: A phase 3, randomised, double-blind, placebo-controlled, multicentre study in 76 hospitals and specialised clinics across North America, Latin America, Europe, and Asia to assess the efficacy and safety of eculizumab in patients with refractory myasthenia gravis.
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Efficacy and Safety of Rituximab Therapy in Neuromyelitis Optica Spectrum Disorders: A Systematic Review and Meta-analysis.

TL;DR: Evidence is provided that rituximab therapy reduces the frequency of NMOSD relapses and neurological disability in patients with NMOSDs, however, the safety profile suggests caution in prescribing ritUXimab as a first-line therapy.
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A significant sex--but not elective cesarean section--effect on mother-to-child transmission of hepatitis C virus infection

TL;DR: The results strongly suggest that women should neither be offered an elective CS nor be discouraged from breast-feeding on the basis of HCV infection alone, and the sex association is an intriguing finding that probably reflects biological differences in susceptibility or response to infection.
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Updated estimate of AQP4-IgG serostatus and disability outcome in neuromyelitis optica

TL;DR: AQP4-IgG–seronegative NMO is less frequent than previously reported and is clinically similar to AQP4–immunoglobulin G–seropositive NMO, and serological tests using recombinant AQP3 antigen are significantly more sensitive than tissue-based IIF for detecting AQP 4-IGG.
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Re-evaluation of the diagnostic criteria for Wilson disease in children with mild liver disease†‡

TL;DR: Urinary copper excretion greater than 40 μg/24 hours is suggestive of Wilson disease in asymptomatic children, whereas the penicillamine challenge test does not have a diagnostic role in this subset of patients.