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Andrea M. Corse

Researcher at Johns Hopkins University School of Medicine

Publications -  64
Citations -  3997

Andrea M. Corse is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Muscle biopsy & Myositis. The author has an hindex of 29, co-authored 60 publications receiving 3306 citations. Previous affiliations of Andrea M. Corse include Bryn Mawr College & Johns Hopkins University.

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A novel autoantibody recognizing 200‐kd and 100‐kd proteins is associated with an immune‐mediated necrotizing myopathy

TL;DR: An anti-200/100-kd specificity defines a subgroup of patients with necrotizing myopathy who previously were considered to be autoantibody negative and should be treated with immunosuppressive therapy.
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Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

James F. Howard, +623 more
- 01 Dec 2017 - 
TL;DR: A phase 3, randomised, double-blind, placebo-controlled, multicentre study in 76 hospitals and specialised clinics across North America, Latin America, Europe, and Asia to assess the efficacy and safety of eculizumab in patients with refractory myasthenia gravis.
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Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy

TL;DR: It is proposed that in cancer-associated myositis, an autoimmune response directed against cancer cross-reacts with regenerating muscle cells, enabling a feed-forward loop of tissue damage and antigen selection and Regulating pathways of antigen expression may provide unrecognized therapeutic opportunities in autoimmune diseases.
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Multifocal motor neuropathy: Response to human immune globulin

TL;DR: It is found that HIg may be an effective therapy for patients with MMN and the range of functional improvement veried from dramatic to mild, with improvement peaking at 2 weeks and lasting for an average of 2 months.
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Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration.

TL;DR: It is hypothesized that PEDF may play important roles in the survival and maintenance of spinal motor neurons in their neuroprotection against acquired insults in postnatal life and should be developed further as a therapeutic strategy for motor neuron diseases such as ALS.