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Renato Mantegazza

Researcher at Carlo Besta Neurological Institute

Publications -  331
Citations -  11716

Renato Mantegazza is an academic researcher from Carlo Besta Neurological Institute. The author has contributed to research in topics: Myasthenia gravis & Medicine. The author has an hindex of 55, co-authored 286 publications receiving 9843 citations. Previous affiliations of Renato Mantegazza include University of Milan & Weizmann Institute of Science.

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Pathogenesis, diagnosis and treatment of Rasmussen encephalitis A European consensus statement

TL;DR: This work proposes formal diagnostic criteria and a therapeutic pathway for the management of RE patients, and summarizes recent data on the pathogenesis, clinical and paraclinical presentation, and therapeutic approaches.
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Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis

TL;DR: To evaluate the ability of mesenchymal stem cells (MSCs), a subset of adult stem cells from bone marrow, to cure experimental autoimmune encephalomyelitis.
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Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

James F. Howard, +623 more
- 01 Dec 2017 - 
TL;DR: A phase 3, randomised, double-blind, placebo-controlled, multicentre study in 76 hospitals and specialised clinics across North America, Latin America, Europe, and Asia to assess the efficacy and safety of eculizumab in patients with refractory myasthenia gravis.
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Expression of transforming growth factor-beta 1 in dystrophic patient muscles correlates with fibrosis. Pathogenetic role of a fibrogenic cytokine.

TL;DR: expression of transforming growth factor-beta 1 in the early stages of Duchenne muscular dystrophy may be critical in initiating muscle fibrosis and antifibrosis treatment could slow progression of the disease, increasing the utility of gene therapy.
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An international, phase III, randomized trial of mycophenolate mofetil in myasthenia gravis

TL;DR: Initiation of mycophenolate mofetil treatment was not superior to placebo in maintaining myasthenia gravis control during a 36-week schedule of prednisone tapering, but MMF was well tolerated and adverse events were consistent with previous studies.