R
Raghu Kalluri
Researcher at University of Texas MD Anderson Cancer Center
Publications - 325
Citations - 89851
Raghu Kalluri is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Angiogenesis. The author has an hindex of 115, co-authored 306 publications receiving 71127 citations. Previous affiliations of Raghu Kalluri include Beth Israel Deaconess Medical Center & Baylor College of Medicine.
Papers
More filters
Journal ArticleDOI
Stage-Specific Action of Matrix Metalloproteinases Influences Progressive Hereditary Kidney Disease
Michael Zeisberg,Mona Khurana,Velidi H. Rao,Dominic Cosgrove,Jean Philippe Rougier,Michelle C. Werner,Charles F. Shield,Zena Werb,Raghu Kalluri +8 more
TL;DR: It is suggested that preserving GBM/extracellular matrix integrity before the onset of proteinuria leads to significant disease protection, but if this window of opportunity is lost, MMP-inhibition at the later stages of Alport disease leads to accelerated glomerular and interstitial fibrosis.
Journal ArticleDOI
Discovery of Double-Stranded Genomic DNA in Circulating Exosomes
Raghu Kalluri,Valerie S. LeBleu +1 more
TL;DR: The discovery of exosomal DNA, studies related to the origin of genomic DNA in exosomes, and its utility in cancer diagnosis and disease monitoring are focused on.
Journal ArticleDOI
Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction
Vicki Plaks,Julie Rinkenberger,Joanne Dai,Margaret L. Flannery,Malin Sund,Keizo Kanasaki,Keizo Kanasaki,Wei Ni,Raghu Kalluri,Zena Werb,Zena Werb +10 more
TL;DR: It is shown that matrix metalloproteinase-9 (MMP9) deficiency causes physiological and placental abnormalities in mice, which mimic features of PE, and that fetal and maternal MMP9 play a role in the development of PE.
Journal ArticleDOI
Blocking Angiotensin II Synthesis/Activity Preserves Glomerular Nephrin in Rats with Severe Nephrosis
Ariela Benigni,Susanna Tomasoni,Elena Gagliardini,Carla Zoja,James A. Grunkemeyer,Raghu Kalluri,Giuseppe Remuzzi +6 more
TL;DR: In this paper, the authors used an accelerated model of experimental nephrosis to assess nephrin gene and protein expression in the kidney and the possible modulating effect of drugs that block angiotensin II (AII) synthesis/activity.
Journal ArticleDOI
Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia
Vesna D. Garovic,Steven J. Wagner,Lydia M. Petrovic,Catherine E. Gray,Pauline de la M. Hall,Hikaru Sugimoto,Raghu Kalluri,Joseph P. Grande +7 more
TL;DR: It is concluded that down-regulation of nephrin and synaptopodin is associated with proteinuria in women with preeclampsia, further supporting a possible role of sFlt-1 in the dysregulation of podocyte foot-process proteins.