R
Raghu Kalluri
Researcher at University of Texas MD Anderson Cancer Center
Publications - 325
Citations - 89851
Raghu Kalluri is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Angiogenesis. The author has an hindex of 115, co-authored 306 publications receiving 71127 citations. Previous affiliations of Raghu Kalluri include Beth Israel Deaconess Medical Center & Baylor College of Medicine.
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Journal ArticleDOI
Loss of p53 and Acquisition of Angiogenic MicroRNA Profile Are Insufficient to Facilitate Progression of Bladder Urothelial Carcinoma in Situ to Invasive Carcinoma
Francisco Ayala de la Peña,Keizo Kanasaki,Megumi Kanasaki,Neelima Tangirala,Genta Maeda,Raghu Kalluri,Raghu Kalluri,Raghu Kalluri +7 more
TL;DR: The results support the notion that activation of angiogenesis and loss of p53 are not sufficient for progression to invasive cancer and identify a new mouse model for bladder cancer that can be used to study factors that determine progression to an invasive phenotype of bladder cancer.
Journal ArticleDOI
Stem Cell Therapies Benefit Alport Syndrome
Valerie S. LeBleu,Hikaru Sugimoto,Thomas M. Mundel,Behzad Gerami-Naini,Elizabeth Finan,Caroline A. Miller,Vincent H. Gattone,Lingge Lu,Charles F. Shield,Judah Folkman,Raghu Kalluri +10 more
TL;DR: In mice lacking the alpha3 chain of type IV collagen, infusion of wild-type bone marrow-derived cells into unconditioned, nonirradiated Col4A3 knockout mice during the late stage of disease significantly improved renal histology and function and significantly improved survival.
Journal ArticleDOI
Drug resistance associated with antiangiogenesis therapy.
TL;DR: The knowledge regarding resistance mechanisms towards angiogenesis inhibitors is still evolving and here some theories are proposed and in some cases experimental evidence is provided.
Journal ArticleDOI
Assembly of Type IV Collagen: INSIGHTS FROM α3(IV) COLLAGEN-DEFICIENT MICE *
Raghu Kalluri,Dominic Cosgrove +1 more
TL;DR: It is proved that expression of α5 is not dependent on the expression ofα3 chain in these tissues and that α5 chain can assemble into basement membranes in the absence of α3 chain, which supports the notion that type IV collagen assembly may be regulated by tissue-specific factors.
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Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
Lamiaa El-Shennawy,Andrew D. Hoffmann,Nurmaa Dashzeveg,Kathleen M. McAndrews,P.J. Mehl,Daphne Cornish,Zihao Yu,Valerie Tokars,Vlad Nicolaescu,Anastasia Tomatsidou,Chengsheng Mao,Christopher Felicelli,Chia-Feng Tsai,Carolina Ostiguin,Yuzhi Jia,Lin Li,Kevin Furlong,Jan Wysocki,Xin Luo,Carolina F. Ruivo,Daniel Batlle,Thomas J. Hope,Yang Shen,Young Kwang Chae,Hui Zhang,Valerie S. LeBleu,Tujin Shi,Suchitra Swaminathan,Yuan Luo,Dominique Missiakas,Glenn Randall,Alexis R. Demonbreun,Michael G. Ison,Raghu Kalluri,Deyu Fang,Huiping Liu +35 more
TL;DR: In this paper , an increase in circulating extracellular vesicles (EVs) that express ACE2 (evACE2) in plasma of COVID-19 patients was associated with severe pathogenesis.