R
Raghu Kalluri
Researcher at University of Texas MD Anderson Cancer Center
Publications - 325
Citations - 89851
Raghu Kalluri is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Angiogenesis. The author has an hindex of 115, co-authored 306 publications receiving 71127 citations. Previous affiliations of Raghu Kalluri include Beth Israel Deaconess Medical Center & Baylor College of Medicine.
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Journal ArticleDOI
Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells
Michael W. Pickup,Philip Owens,Agnieszka E. Gorska,Anna Chytil,Fei Ye,Chanjuan Shi,Valerie M. Weaver,Raghu Kalluri,Harold L. Moses,Sergey V. Novitskiy +9 more
TL;DR: Elevated G-CSF contributes to tumor progression through promoting increases in infiltration of neutrophil-like cells with high immunosuppressive activity in aggressive PDAC, providing an avenue for a neoadjuvant therapeutic approach for this devastating disease.
Posted ContentDOI
Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
Daniel J. McGrail,Jianli Dai,Kathleen M. McAndrews,Raghu Kalluri,Raghu Kalluri,Raghu Kalluri +5 more
TL;DR: In this article, the authors quantify the spread rate of COVID19 before and after national social distancing measures were implemented in 26 nations and compare this to the changes in COVID-19 spread rate over equivalent time periods in 27 nations that did not enact social distance policies.
Journal ArticleDOI
Type IV collagen α6 chain‐derived noncollagenous domain 1 (α6(IV)NC1) inhibits angiogenesis and tumor growth
Thomas M. Mundel,Anna Maija Yliniemi,Yohei Maeshima,Hikaru Sugimoto,Mark W. Kieran,Raghu Kalluri +5 more
TL;DR: The NC1 domain of the α6 chain of type IV collagen (α6NC1) is an endogenous inhibitor of angiogenesis and tumor growth and is associated with significantly diminished microvascular density.
Journal ArticleDOI
Differential expression of type IV collagen isoforms in rat glomerular endothelial and mesangial cells.
TL;DR: It is demonstrated that GMC might contribute to mesangial matrix expansion, mediated by alpha 1(IV) collagen, while GEndCmight contribute to thickening of GBM, mediatedBy alpha 3(IV), in patients with diabetic nephropathy.
Journal ArticleDOI
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
Carolina F. Ruivo,Nuno Bastos,Bárbara Adem,Inês A. Batista,Cecília Durães,Carlos A. Melo,Stephanie Anais Castaldo,Francisco J. Campos-Laborie,Pedro Moutinho-Ribeiro,B Morão,Ana Costa-Pinto,Soraia Silva,Hugo Osório,Sergio Ciordia,José Luis Costa,David W. Goodrich,Bruno Cavadas,Luísa Pereira,Tony Kouzarides,Guilherme Macedo,Rui Maio,Fátima Carneiro,Marília Cravo,Raghu Kalluri,José Carlos Machado,Sonia A. Melo +25 more
TL;DR: PDAC tumours establish a cooperation network mediated by EVs that is led by CSC and agrin, which allows tumours to adapt and thrive, and targeting agrin could make targeted therapy possible for patients with PDAC.