R
Raghu Kalluri
Researcher at University of Texas MD Anderson Cancer Center
Publications - 325
Citations - 89851
Raghu Kalluri is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Angiogenesis. The author has an hindex of 115, co-authored 306 publications receiving 71127 citations. Previous affiliations of Raghu Kalluri include Beth Israel Deaconess Medical Center & Baylor College of Medicine.
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Journal ArticleDOI
Acute Kidney Injury Instigates Malignant Renal Cell Carcinoma via CXCR2 in Mice with Inactivated Trp53 and Pten in Proximal Tubular Kidney Epithelial Cells.
Xunian Zhou,Fei Xiao,Hikaru Sugimoto,Bingrui Li,Kathleen M. McAndrews,Raghu Kalluri,Raghu Kalluri,Raghu Kalluri +7 more
TL;DR: Kusmartsev et al. as mentioned in this paper found a role for CXCL1/CXCR2 and the tumor microenvironment in the development of Renal Cell Carcinoma (RCC) in mice.
Journal ArticleDOI
An evolving function of DNA-containing exosomes in chemotherapy-induced immune response.
Paul Kurywchak,Raghu Kalluri +1 more
TL;DR: It is found that double-stranded DNA in small vesicles can launch inflammation pathways in immune cells through the cytosolic DNA sensor AIM2.
Journal ArticleDOI
Multifunctional Applications of Engineered Extracellular Vesicles in the Treatment of Cancer.
TL;DR: Extracellular vesicles (EVs) are key players of intercellular communication in the physiological and pathological setting as mentioned in this paper, and they can be loaded with therapeutic agents and modified to display tumor-targeting molecules.
Journal ArticleDOI
Waking up dormant tumors
TL;DR: A systemic interaction between cancer cells and distant bone marrow cells to support the growth of otherwise indolent tumor cells at a secondary site is demonstrated, raising thought-provoking questions regarding the involvement of stromal cells in maintaining metastatic dormancy.
Posted ContentDOI
A subgroup of mitochondrial extracellular vesicles discovered in human melanoma tissues are detectable in patient blood
Su Chul Jang,Rossella Crescitelli,Aleksander Cvjetkovic,Valerio Belgrano,Roger Olofsson Bagge,Johanna L. Höög,Karin Sundfeldt,Takahiro Ochiya,Raghu Kalluri,Jan Lötvall +9 more
TL;DR: The findings show that tumor tissues are enriched in EVs with mitochondrial proteins and enzymatic activity, and these EVs can be detected in blood.