R
Raghu Kalluri
Researcher at University of Texas MD Anderson Cancer Center
Publications - 325
Citations - 89851
Raghu Kalluri is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Angiogenesis. The author has an hindex of 115, co-authored 306 publications receiving 71127 citations. Previous affiliations of Raghu Kalluri include Beth Israel Deaconess Medical Center & Baylor College of Medicine.
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Journal ArticleDOI
Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner
Liang Xie,Michael Duncan,Michael Duncan,Jessica C. Pahler,Hikaru Sugimoto,Margot Martino,Julie C. Lively,Julie C. Lively,Thomas M. Mundel,Mary A. Soubasakos,Kristofer Rubin,Kristofer Rubin,Takaaki Takeda,Masahiro Inoue,Jack Lawler,Richard O. Hynes,Douglas Hanahan,Douglas Hanahan,Raghu Kalluri +18 more
TL;DR: The results demonstrate that EAIs are part of a balance mechanism regulating tumor angiogenesis, serving as intrinsic microenvironmental barriers to tumorigenesis.
Journal ArticleDOI
Transcriptional regulation of epithelial-mesenchymal transition.
TL;DR: Results suggest that this novel protein-DNA complex that is essential for transcription of fibroblast-specific protein 1 (FSP1) and sufficient to induce early EMT events is an important regulator of the EMT transcriptome.
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Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis
Timothy P. Cleland,Timothy P. Cleland,Elena R. Schroeter,Leonid Zamdborg,Wenxia Zheng,Ji Eun Lee,Ji Eun Lee,John C. Tran,Marshall Bern,Michael Duncan,Valerie S. LeBleu,Dorothy R. Ahlf,Paul M. Thomas,Raghu Kalluri,Neil L. Kelleher,Mary Higby Schweitzer,Mary Higby Schweitzer +16 more
TL;DR: Test the hypothesis that dinosaur cortical bone fragments recovered after demineralization are endogenous and thus retain proteins in common with extant archosaur blood vessels that can be detected with high-resolution mass spectrometry and confirmed by immunofluorescence and two lines of evidence support this hypothesis.
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Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer.
Kathleen M. McAndrews,Fei Xiao,Antonios Chronopoulos,Valerie S. LeBleu,Valerie S. LeBleu,Fernanda G. Kugeratski,Raghu Kalluri,Raghu Kalluri,Raghu Kalluri +8 more
TL;DR: In this article, a non-autologous exosomes can encapsulate CRISPR/Cas9 plasmid DNA via commonly available transfection reagents and can be delivered to recipient cancer cells to induce targeted gene deletion.
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A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure.
TL;DR: The domain-specific interaction between usherin and type IV collagen appears essential to usherin stability in vivo, and loss of this interaction may result in Usher pathology in humans.