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Raghu Kalluri

Researcher at University of Texas MD Anderson Cancer Center

Publications -  325
Citations -  89851

Raghu Kalluri is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Angiogenesis. The author has an hindex of 115, co-authored 306 publications receiving 71127 citations. Previous affiliations of Raghu Kalluri include Beth Israel Deaconess Medical Center & Baylor College of Medicine.

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Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth.

TL;DR: Fibulin-1 suppression of HT1080 tumor growth is associated with diminished angiogenesis and also enhanced apoptosis of endothelial cells and tumor cells, and fibulin-5 inhibits tumorAngiogenesis with a minimal anti-apoptotic affect.
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Goodpasture syndrome involving overlap with Wegener's granulomatosis and anti-glomerular basement membrane disease

TL;DR: The patient reported here had the unusual combination of c-ANCA antibodies with anti-GBM disease, and this association raises complex questions regarding the pathogenesis of this type of renal injury.
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Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis

TL;DR: NM-3 is a well-tolerated angiogenesis inhibitor that significantly increases the efficacy of existing antineoplastic agents and shows synergistic antiproliferative activity when treated with NM-3 in combination with 5-fluorouracil.
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NM-3, an Isocoumarin, Increases the Antitumor Effects of Radiotherapy without Toxicity

TL;DR: The present studies demonstrate that NM-3 is cytotoxic to human umbilical vein endothelial cells (HUVECs) but not to Lewis lung carcinoma (LLC) cells nor Seg-1, esophageal adenocarcinoma cells, in clonogenic survival assays.
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Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017

TL;DR: The conclusion of the ISEV Workshop on extracellular vesicle biomarkers was that more effort focused on pre-analytical issues and benchmarking of isolation methods is needed to strengthen collaborations and advance more effective biomarkers.