R
Raymond R. Townsend
Researcher at University of Pennsylvania
Publications - 706
Citations - 47086
Raymond R. Townsend is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Blood pressure & Kidney disease. The author has an hindex of 84, co-authored 673 publications receiving 39096 citations. Previous affiliations of Raymond R. Townsend include University of Texas Medical Branch & University of California, San Francisco.
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Journal ArticleDOI
A unified sample preparation protocol for proteomic and genomic profiling of cervical swabs to identify biomarkers for cervical cancer screening.
Janet S. Rader,James P. Malone,Julia Gross,Petra Gilmore,Rebecca A. Brooks,Loan Nguyen,Dan L. Crimmins,Sheng Feng,Jason D. Wright,Nicholas F. Taylor,Israel Zighelboim,Margo C. Funk,Phyllis C. Huettner,Jack H. Ladenson,David Gius,Raymond R. Townsend +15 more
TL;DR: HNRPA2B1 was identified as a biomarker candidate with increased expression in cancer compared to normal cervix and validated by Western blot, and the most frequent pathways represented by the combined dataset were: cell cycle: G2/M DNA damage checkpoint regulation; aryl hydrocarbon receptor signaling; p53 signaling; and the ER stress pathway.
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Use of diuretics with ACE inhibitors or angiotensin receptor blockers and NSAIDs increases the risk of acute kidney injury
TL;DR: Medications contribute to AKI whether administered in hospital such as aminoglycoside antibiotics, or when prescribed for outpatients, such as non-steroidal anti-inflammatory drugs (NSAIDs) whose adverse effects are seen more often to involve the gastrointestinal tract rather than kidneys.
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The Role of Glomerular Epithelial Injury in Kidney Function Decline in Patients With Diabetic Kidney Disease in the TRIDENT Cohort.
Matthew B. Palmer,Amin Abedini,Casey Jackson,Shira J. Blady,Shatakshee Chatterjee,Katie Marie Sullivan,Raymond R. Townsend,Jens Brodbeck,Salem Almaani,Anand Srivastava,Rupali S. Avasare,Michael W. Ross,Amy K. Mottl,Christos Argyropoulos,Jonathan J. Hogan,Katalin Susztak +15 more
TL;DR: In this article, an interim analysis of 62 patients diagnosed with biopsy-confirmed kidney disease from the multicenter TRIDENT (Transformative Research in Diabetic Nephropathy) study was performed.
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Separation of partially desialylated branched oligosaccharide isomers containing α(2←3)- and α(2←6)-linked Neu5Ac
TL;DR: The studies show that chemical desialylation and HPAEC is a useful approach to prepare and identify all possible sialylated branch isomers and should prove useful for defining the branch specificity of sIALyltransferases and sialidases.