R
Raymond R. Townsend
Researcher at University of Pennsylvania
Publications - 706
Citations - 47086
Raymond R. Townsend is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Blood pressure & Kidney disease. The author has an hindex of 84, co-authored 673 publications receiving 39096 citations. Previous affiliations of Raymond R. Townsend include University of Texas Medical Branch & University of California, San Francisco.
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Proteomic Analysis of Anoxia Tolerance in the Developing Zebrafish Embryo
TL;DR: These studies in an intact embryo highlight proteomic components of an adaptive response to anoxia in a model organism amenable to genetic analysis to permit further mechanistic insight into the phenomenon of anxia tolerance.
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Serum Calcification Propensity and Clinical Events in CKD.
Joshua D. Bundy,Xuan Cai,Rupal Mehta,Julia J. Scialla,Ian H. de Boer,Chi-yuan Hsu,Alan S. Go,Mirela Dobre,Jing Chen,Panduranga S. Rao,Mary B. Leonard,James P. Lash,Geoffrey A. Block,Raymond R. Townsend,Harold I. Feldman,Edward R Smith,Andreas Pasch,Tamara Isakova +17 more
TL;DR: Higher serum calcification propensity is associated with atherosclerotic cardiovascular disease events, ESKD, and all-cause mortality among patients with CKD stages 2-4, but this association was not independent of kidney function.
Journal Article
Abstract 14934: Heart Failure, Left Ventricular Remodeling, and Circulating Nitric Oxide Metabolites
Julio A. Chirinos,Scott Akers,Lien Trieu,Harry Ischiropoulos,Paschalis-Thomas Doulias,Ali Tariq,Izzah Vassim,Maheswara R Koppula,Amer Ahmed Syed,Haideliza Soto-Calderon,Raymond R. Townsend,Thomas P. Cappola,Kenneth B. Margulies,Payman Zamani +13 more
TL;DR: HFpEF, but not HFrEF, is associated with reduced plasma NOM, suggesting greater endothelial dysfunction, enhanced clearance, or deficient dietary ingestion of inorganic nitrate may underlie the salutary effects of in organic nitrate supplementation demonstrated in recent clinical trials in HFpEF.
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Determination of the sialylation pattern of human fibrinogen glycopeptides with fast atom bombardment.
TL;DR: Sialylated biantennary glycopeptides from human fibrinogen were analyzed with fast atom bombardment mass spectrometry and revealed a linear relationship between ion abundance and molar fraction.
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Isosorbide Dinitrate, With or Without Hydralazine, Does Not Reduce Wave Reflections, Left Ventricular Hypertrophy, or Myocardial Fibrosis in Patients With Heart Failure With Preserved Ejection Fraction
Payman Zamani,Scott Akers,Haideliza Soto-Calderon,Melissa Beraun,Maheswara R Koppula,Swapna Varakantam,Deepa Rawat,Prithvi Shiva-Kumar,Philip Haines,Philip Haines,Jesse Chittams,Raymond R. Townsend,Walter R Witschey,Patrick Segers,Julio A. Chirinos +14 more
TL;DR: ISDN, with or without hydralazine, does not exert beneficial effects on RM, left ventricular remodeling, or submaximal exercise and is poorly tolerated, while ISDN+hydral appears to have deleterious effects onRM, myocardial remodelling, and sub maximal exercise.