R
Raymond R. Townsend
Researcher at University of Pennsylvania
Publications - 706
Citations - 47086
Raymond R. Townsend is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Blood pressure & Kidney disease. The author has an hindex of 84, co-authored 673 publications receiving 39096 citations. Previous affiliations of Raymond R. Townsend include University of Texas Medical Branch & University of California, San Francisco.
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Journal ArticleDOI
Use of Measures of Inflammation and Kidney Function for Prediction of Atherosclerotic Vascular Disease Events and Death in Patients With CKD: Findings From the CRIC Study
Richard Amdur,Harold I. Feldman,Elizabeth A. Dominic,Amanda H. Anderson,Srinivasan Beddhu,Mahboob Rahman,Myles Wolf,Muredach P. Reilly,Akinlolu Ojo,Raymond R. Townsend,Alan S. Go,Jiang He,Dawei Xie,Sally Thompson,Matthew J. Budoff,Scott E. Kasner,Paul L. Kimmel,John W. Kusek,Dominic S. Raj,Jeffrey C. Fink,Lawrence J. Appel,James P. Lash +21 more
TL;DR: Traditional cardiovascular risk estimates could be improved by adding markers of inflammation and measures of kidney function to traditional estimation tools, which are independently associated with incident ASVD events and death in patients with CKD.
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Different modes of ligand binding to the hepatic galactose/N-acetylgalactosamine lectin on the surface of rabbit hepatocytes.
TL;DR: There were many more total binding sites for TRI or di-tris-lac on the surface of rabbit hepatocytes than there were for asialoorosomucoid, although the dissociation constants were similar for all three ligands.
Journal ArticleDOI
Two Cys residues essential for von Willebrand factor multimer assembly in the Golgi
Angie R. Purvis,Julia Gross,Luke T. Dang,Ren-Huai Huang,Milan Kapadia,Raymond R. Townsend,J. Evan Sadler +6 more
TL;DR: The cysteines involved in multimer assembly were characterized by using a VWF construct that encodes the N-terminal D1D2D′D3 domains, and it is reported that Cys1099 and Cys1142 are essential for the oxidoreductase mechanism of VWF multimerization.
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Prevalence, Predictors, and Outcomes of Pulmonary Hypertension in CKD
Sankar D. Navaneethan,Jason Roy,Kelvin Tao,Carolyn Brecklin,Jing Chen,Rajat Deo,John M. Flack,Akinlolu O. Ojo,Theodore J Plappert,Dominic S. Raj,Ghulam Saydain,James H. Sondheimer,Ruchi Sood,Susan Steigerwalt,Raymond R. Townsend,Raed A. Dweik,Mahboob Rahman +16 more
TL;DR: PH and higher TRV and PASP (echocardiographic measures of PH) are associated with adverse outcomes in CKD and future studies may explain the mechanisms that underlie these findings.
Journal ArticleDOI
Purification and structure-function analysis of native, pngase f-treated, and endo-beta -galactosidase-treated chip28 water channels
A. N. Van Hoek,Michael C. Wiener,Jean-Marc Verbavatz,Dennis Brown,Peter H. Lipniunas,Raymond R. Townsend,Alan S. Verkman +6 more
TL;DR: The role of glycosylation in CHIP28 structure and function was determined and freeze-fracture electron microscopy with rotary shadowing indicated that native and deglycosylatedCHIP28 assembled as tetramers in reconstituted proteoliposomes.