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Rebecca Schwenk
Researcher at Goethe University Frankfurt
Publications - 5
Citations - 63
Rebecca Schwenk is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Cell adhesion molecule & Endothelial stem cell. The author has an hindex of 3, co-authored 5 publications receiving 40 citations.
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Journal ArticleDOI
Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing
Edna Bode,Antje K. Heinrich,Merle Hirschmann,Desalegne Abebew,Yan-Ni Shi,Tien Duy Vo,Frank Wesche,Yi-Ming Shi,Peter Grün,Svenja Simonyi,Nadine Keller,Yvonne Engel,Sebastian L Wenski,Reuel Bennet,Sophie Beyer,Iris Bischoff,Anthony Buaya,Sophie C. Brandt,Ibrahim Cakmak,Harun Cimen,Simone Eckstein,Denia Frank,Robert Fürst,Martin Gand,Gerd Geisslinger,Selcuk Hazir,Marina Henke,Ralf Heermann,Virginie Lecaudey,Wilhelm Schäfer,Susanne Schiffmann,Anja Schüffler,Rebecca Schwenk,Marisa Skaljac,Eckhard Thines,Marco Thines,Thomas Ulshöfer,Andreas Vilcinskas,Thomas A. Wichelhaus,Helge B. Bode +39 more
TL;DR: This easyPACId approach (easy Promoter Activated Compound Identification) facilitates NP identification due to low interference from other NPs and allows direct bioactivity testing of supernatants containing secreted NPs, without laborious purification.
Journal ArticleDOI
Narciclasine exerts anti-inflammatory actions by blocking leukocyte–endothelial cell interactions and down-regulation of the endothelial TNF receptor 1
Anna Stark,Rebecca Schwenk,Gesine Wack,Gabriele Zuchtriegel,Melissa G. Hatemler,Jacqueline Bräutigam,Achim Schmidtko,Christoph A. Reichel,Iris Bischoff,Robert Fürst +9 more
TL;DR: This study highlights narciclasine as an interesting anti‐inflammatory compound that effectively inhibits the interaction of leukocytes with ECs by blocking endothelial activation processes and shows that the observed inhibitory action of narcIClasine on TNF‐triggered signaling pathways is based on the loss of TNFR1.
Journal ArticleDOI
The pretubulysin-induced exposure of collagen is caused by endothelial cell retraction that results in an increased adhesion and decreased transmigration of tumor cells.
TL;DR: This study provides, at least in part, an explanation for the anti-metastatic potential of PT.
Journal ArticleDOI
The vacuolar-type ATPase inhibitor archazolid increases tumor cell adhesion to endothelial cells by accumulating extracellular collagen.
Betty Luong,Rebecca Schwenk,Jacqueline Bräutigam,Rolf Müller,Dirk Menche,Iris Bischoff,Robert Fürst +6 more
TL;DR: It is demonstrated that the inhibition of v-ATPase by archazolid induces a pro-adhesive phenotype in endothelial cells that promotes their interaction with cancer cells, whereas the transmigration of tumor cells was reduced.
Journal ArticleDOI
Back Cover: Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing (Angew. Chem. Int. Ed. 52/2019)
Edna Bode,Antje K. Heinrich,Merle Hirschmann,Desalegne Abebew,Yan-Ni Shi,Tien Duy Vo,Frank Wesche,Yi-Ming Shi,Peter Grün,Svenja Simonyi,Nadine Keller,Yvonne Engel,Sebastian L Wenski,Reuel Bennet,Sophie Beyer,Iris Bischoff,Anthony Buaya,Sophie C. Brandt,Ibrahim Cakmak,Harun Cimen,Simone Eckstein,Denia Frank,Robert Fürst,Martin Gand,Gerd Geisslinger,Selcuk Hazir,Marina Henke,Ralf Heermann,Virginie Lecaudey,Wilhelm Schäfer,Susanne Schiffmann,Anja Schüffler,Rebecca Schwenk,Marisa Skaljac,Eckhard Thines,Marco Thines,Thomas Ulshöfer,Andreas Vilcinskas,Thomas A. Wichelhaus,Helge B. Bode +39 more