S
Sebastian L Wenski
Researcher at Goethe University Frankfurt
Publications - 13
Citations - 178
Sebastian L Wenski is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Xenorhabdus & Photorhabdus. The author has an hindex of 4, co-authored 8 publications receiving 40 citations.
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Journal ArticleDOI
A microbiome-dependent gut-brain pathway regulates motivation for exercise.
Lenka Dohnalová,Patrick Lundgren,Jamie R E Carty,Nitsan Goldstein,Sebastian L Wenski,Pakjira Nanudorn,Sirinthra Thiengmag,Kuei-Pin Huang,Lev Litichevskiy,Hélène Descamps,Karthikeyani Chellappa,Ana Glassman,Susanne Kessler,Jihee Kim,Timothy O. Cox,Oxana Dmitrieva-Posocco,Andrea C. Wong,Erik L. Allman,Soumita Ghosh,Nitika Sharma,Kasturi Sengupta,Belinda K. Cornes,Nitai Dean,Gary A. Churchill,Tejvir S. Khurana,Mark A. Sellmyer,Garret A. FitzGerald,Andrew D. Patterson,Joseph A. Baur,Amber L. Alhadeff,Eric J. N. Helfrich,Maayan Levy,J. Nicholas Betley,Christoph A. Thaiss +33 more
Journal ArticleDOI
Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing
Edna Bode,Antje K. Heinrich,Merle Hirschmann,Desalegne Abebew,Yan-Ni Shi,Tien Duy Vo,Frank Wesche,Yi-Ming Shi,Peter Grün,Svenja Simonyi,Nadine Keller,Yvonne Engel,Sebastian L Wenski,Reuel Bennet,Sophie Beyer,Iris Bischoff,Anthony Buaya,Sophie C. Brandt,Ibrahim Cakmak,Harun Cimen,Simone Eckstein,Denia Frank,Robert Fürst,Martin Gand,Gerd Geisslinger,Selcuk Hazir,Marina Henke,Ralf Heermann,Virginie Lecaudey,Wilhelm Schäfer,Susanne Schiffmann,Anja Schüffler,Rebecca Schwenk,Marisa Skaljac,Eckhard Thines,Marco Thines,Thomas Ulshöfer,Andreas Vilcinskas,Thomas A. Wichelhaus,Helge B. Bode +39 more
TL;DR: This easyPACId approach (easy Promoter Activated Compound Identification) facilitates NP identification due to low interference from other NPs and allows direct bioactivity testing of supernatants containing secreted NPs, without laborious purification.
Journal ArticleDOI
Fabclavine diversity in Xenorhabdus bacteria
Sebastian L Wenski,Harun Cimen,Natalie Berghaus,Sebastian W. Fuchs,Selcuk Hazir,Helge B. Bode +5 more
TL;DR: This work lays the foundation for the rapid fabclavine identification and dereplication as the basis for future work of this widespread and bioactive SM class.
Journal ArticleDOI
Nematode-Associated Bacteria: Production of Antimicrobial Agent as a Presumptive Nominee for Curing Endodontic Infections Caused by Enterococcus faecalis
Hicran Dönmez Özkan,Harun Cimen,Derya Ulug,Sebastian L Wenski,Senem Yiğit Özer,Murat Telli,Neriman Aydin,Helge B. Bode,Selcuk Hazir +8 more
TL;DR: Fabclavine in liquid form or preferably as a paste or gel formulation is a promising alternative intracanal medicament and leads to over-expression by induction or a knock-out by non-induction which resulted in a bioactive and non-bioactive mutant.
Journal ArticleDOI
Complex peptide natural products: Biosynthetic principles, challenges and opportunities for pathway engineering
TL;DR: In this paper , the authors compare the key principles of peptide biosynthetic pathways and compare the different biochemical strategies to install the most frequently encountered peptide modifications, and the influence of the fundamentally different biosynthesis principles on past, current and future engineering approaches is illustrated.