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Richard S. Spielman
Researcher at University of Pennsylvania
Publications - 130
Citations - 16030
Richard S. Spielman is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Gene & Allele. The author has an hindex of 48, co-authored 121 publications receiving 15707 citations. Previous affiliations of Richard S. Spielman include April.
Papers
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Journal ArticleDOI
Restriction fragment polymorphisms of the HLA-DR, HLA-DQ, and insulin gene regions in IDDM: the GAW5 data.
Nancy J. Cox,K. J. Gogolin,V. J. Horvath,David F. Barker,E.C. Wright,T. Tran,Mark H. Skolnick,B. O. Boehm,K. Fehsel,J. Bertrams,T. W. Hodge,R. T. Acton,J. McGill,Steven C. Elbein,M. A. Permutt,C. de Preval,P. Avoustin,A. Cambon‐Thomsen,David M. Robinson,Susan L. Holbeck,Gerald T. Nepom,Peter M. Schneider,Christian Rittner,H. Toyoda,Jerome I. Rotter,Richard S. Spielman +25 more
TL;DR: DNA data on members of 94 families with two or more IDDM sibs constitute the largest such sample available, and are available on request.
Journal Article
Registers for the detection and prevention of genetic disease
TL;DR: Book of registers for the detection and prevention of genetic disease, as an amazing reference becomes what you need to get, as a source that may involve the facts, opinion, literature, religion, and many others are the great friends to join with.
Journal ArticleDOI
An Approach for Identifying Simple Sequence Repeat DNA Polymorphisms Near Cloned cDNAs and Genes: Linkage Studies of the Islet Amyloid Polypeptide/Amylin and Liver Glycogen Synthase Genes and NIDDM
Vita Gambino,Stephan Menzel,Jeffrey B. Trabb,Kun San Xiang,Tom H. Lindner,Aymeric Louït,E. X. Chen,Laurie E. Mereu,Hiroto Furuta,Naoko Iwasaki,Makiko Kawamura,Yasue Omori,Hannes Rietzsch,Jan Schulze,Hans Egbert Schröder,Patrick Concannon,Craig L. Hanis,Richard S. Spielman,Kazuya Yamagata,Nancy J. Cox,Graeme I. Bell +20 more
TL;DR: An approach for identifying highly polymorphic markers near candidate genes that utilizes the emerging physical map of the human genome is described and used to identify a marker for the islet amyloid polypeptide gene on chromosome 12.
Journal ArticleDOI
The TDT is a statistically valid test: comments on Wittkowski and Liu.
Journal ArticleDOI
Segregation of HLA in families with oral clefts: evidence against linkage between isolated cleft palate and HLA.
Don C. Van Dyke,Don C. Van Dyke,Allen S. Goldman,Allen S. Goldman,Richard S. Spielman,Chester M. Zmijewski,John M. Opitz +6 more
TL;DR: In 15 sibships with two or more affected sibs, cleft palate, and parental HLA haplotypes assorted independently in the affected sIBs, providing evidence against close linkage of this phenotype.